New Delhi: SARS-CoV-2 can infect a higher proportion of pregnant women and the infected women need immediate medical attention, said a study by the Indian Council of Medical Research (ICMR). It was the first study released by ICMR on adverse outcomes of severe COVID-19 disease in pregnant women. ICMR conducted the study in collaboration with other government institutes and hospitals on pregnant women in Maharashtra.
The data is based on the PregCovid registry that collects information in near real-time on pregnant and post-partum women with laboratory confirmation of COVID from 19 medical colleges across the state of Maharashtra.
The Data of 4,203 pregnant women collected during the first wave of the COVID-19 pandemic (March 2020-January 2021) was analysed.
There were 3,213 live births, 77 miscarriages and 834 undelivered pregnancies. The proportion of pregnancy/foetal loss including stillbirths was six per cent. Five hundred and thirty-four women (13 per cent) were symptomatic, of which 382 (72 per cent) had mild, 112 (21 per cent) had moderate, and 40 (7.5 per cent) had severe disease. The most common complication was preterm delivery (528, 16.3 per cent) and hypertensive disorders in pregnancy (328, 10.1 per cent). A total of 158 (3.8 per cent) pregnant and post-partum women required intensive care, of which 152 (96 per cent) were due to COVID-19 related complications, reads the study by ICMR. According to the study the high fatality was reported in Pune and Marathwada.
“The overall case fatality rate (CFR) in pregnant and post-partum women with COVID-19 was 0.8 per cent (34/4203). Higher CFR was observed in Pune (9/853, 1.1 per cent), Marathwada (4/351, 1.1 per cent) regions as compared to Vidarbha (9/1155, 0.8 per cent), Mumbai Metropolitan (11/1684, 0.7 per cent), and Khandesh (1/160, 0.6 per cent) regions. “Comorbidities of anaemia, tuberculosis and diabetes mellitus were associated with maternal deaths,” the study found.
This is the first large-scale report of systematically collected, multicentre data on the clinical presentation, pregnancy outcomes and maternal deaths amongst women with COVID-19 in Maharashtra, India. The proportion of symptomatic COVID-19 women in our study was 12.7 per cent, a number consistent with that reported earlier from the same cohort18, the study said.
“Our analysis suggests that SARS-CoV-2 may infect a higher proportion of pregnant women, and when symptomatic, a large proportion can develop moderate-to-severe diseases. Therefore, pregnant women with COVID-19 need immediate medical attention from the healthcare system in India,” it said.
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NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (Water, Sanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollution, waste management, plastic ban, manual scavenging and sanitation workers and menstrual hygiene.