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Novavax COVID Vaccine Candidate Shows Overall 90 Per Cent Efficacy: Study

The COVID-19 vaccine was about 90 per cent effective overall and preliminary data showed it was safe, Novavax said

Novavax COVID Vaccine Candidate Shows Overall 90 Per Cent Efficacy: Study
Highlights
  • The efficacy result is based on study done in the US and Mexico
  • The study involved nearly 30,000 people aged 18 and above
  • Two-thirds received two doses of the vaccine, three weeks apart

Washington: Vaccine maker Novavax said on Monday (June 14) its shot was highly effective against COVID-19 and also protected against variants in a large, late-stage study in the US and Mexico. The vaccine was about 90 per cent effective overall and preliminary data showed it was safe, the company said. While demand for COVID-19 shots in the US has dropped off dramatically, the need for more vaccines around the world remains critical. The Novavax vaccine, which is easy to store and transport, is expected to play an important role in boosting vaccine supplies in the developing world. That help is still months away, however.

Also Read: Reduction In COVID-19 Vaccine Wastage Will Ensure Enhanced Vaccination: Government

The company says it plans to seek authorization for the shots in the US, Europe and elsewhere by the end of September and be able to produce up to 100 million doses a month by then.

Many of our first doses will go to low- and middle-income countries, and that was the goal to begin with, Novavax Chief Executive Stanley Erck told The Associated Press.

While more than half of the US population has had at least one COVID-19 vaccine dose, less than 1 percent of people in the developing world have had one shot, according to Our World In Data. Novavax’s study involved nearly 30,000 people ages 18 and up in the US and Mexico. Two-thirds received two doses of the vaccine, three weeks apart, and the rest got dummy shots. There were 77 cases of COVID-19 – 14 in the group that got the vaccine and the rest were in volunteers who received dummy shots. None in the vaccine group had moderate or severe disease, compared to 14 in the placebo group. The vaccine was similarly effective against several variants including the one first detected in the U.K. that’s dominant in the US, and in high-risk populations including the elderly and people with other health problems. Side effects were mostly mild-tenderness and pain at the injection site. There were no reports of unusual blood clots or heart problems, Mr Erck said.

Novavax reported the results in a press release and plans to publish in a medical journal, where it will be vetted by independent experts. The Maryland-based company previously released findings from smaller studies in Britain and South Africa.

Also Read: No Need To Vaccinate People Who Had Documented COVID-19 Infection, Suggests Health Experts

COVID-19 vaccines train the body to recognize the coronavirus, especially the spike protein that coats it, and get ready to fight the virus off. The Novavax vaccine is made with lab-grown copies of that protein. That’s different from some of the other vaccines now widely used, which include genetic instructions for the body to make its own spike protein. The Novavax vaccine can be stored in standard refrigerators, making it easier to distribute. Novavax previously announced manufacturing delays due to supply shortages.

The company now expects to reach production of 100 million doses a month by the end of September and 150 million doses a month by December. The company has committed to supplying 110 million doses to the US over the next year and a total of 1.1 billion doses to developing countries.

Also Read: Unplanned Vaccination Can Promote Mutant Strains Of Coronavirus: Health Experts In Report To PM

In May, vaccines alliance Gavi announced it had signed an agreement to buy 350 million doses of Novavax’s vaccine, with deliveries estimated to begin in the third quarter. COVAX, the global initiative to provide vaccines to countries, is facing a critical shortage of vaccines after its biggest supplier in India suspended exports until the end of the year, Novavax has been working on developing vaccines for more than three decades, but hasn’t brought one to market. The company’s coronavirus vaccine work is partly funded by the US government.

Also Read: Must Work With WHO And World Trade Organisation For Easy Access Of COVID-19 Vaccines: France President

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

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