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Both Pfizer, Moderna Vaccines Effective On B.1.617 COVID-19 Strain: US Study

The study which is yet to be published in a peer-reviewed journal shows that the newly identified SARS-CoV-2 variants identified in India are neutralised well by antibodies in individuals vaccinated with Pfizer and Moderna vaccines

Both Pfizer, Moderna Vaccines Effective On B.1.617 COVID-19 Strain: US Study
Highlights
  • Researchers worked on blood samples from people who were vaccinated
  • The blood drawn was exposed in a lab to engineered pseudovirus particles
  • Pseudovirus particles contained mutations in spike region of coronavirus

Washington: COVID-19 vaccines developed by Pfizer and Moderna work against B.1.617 variant of the virus that was first identified in India, according to a new study. The study shows that the newly identified SARS-CoV-2 variants identified in India are neutralised well by antibodies in individuals vaccinated with both vaccines. “This finding predicts that even though the new variants are highly transmissible, vaccinated individuals will be protected from infection with the new variants,” senior author Professor Nathaniel R Landau told ANI on Tuesday (May 18).

Also Read: Amid Looming Shortfall Of Doses, UNICEF Calls For Global, Equitable Distribution Of COVID-19 Vaccines

The lab-based study, which was carried out by the NYU Grossman School of Medicine and NYU Langone Center, is considered preliminary. Professor Landau and the team of researchers worked on blood samples from people who were vaccinated with Pfizer or Moderna vaccines. The blood drawn was exposed in a lab to engineered pseudovirus particles that contained mutations in the “spike” region of the coronavirus, which were particular to either the B.1.617 or B.1.618 variants, first found in India. And this mixture was exposed to lab-grown cells, to see how many would become infected. Researchers found an almost four-fold reduction in the amount of neutralising antibodies Y-shaped proteins the immune system creates to stop pathogens from invading cells.

People should get vaccinated. It will protect them, their family members and will slow the emergence of new variants, Professor Landau asserted.

Also Read: Booster Effect Even At Six Months, Don’t Worry: Experts On Covishield Dose Gap

President Biden announced on Monday (May 17) that he will export 20 million doses of vaccines from Pfizer In., Moderna Inc and Johnson & Johnson, on top of 60 million AstraZeneca doses he had already planned to give to other countries. During a Tuesday White House briefing, Dr Anthony Fauci said initial studies indicated the Pfizer-BioNTech and Moderna vaccines are “at least partially and probably quite protective” against serious illness, hospitalisation and death, “indicating another very strong reason why we should be getting vaccinated”.

Also Read: Vaccinating As Many People As Possible Should Be The Top Priority, Says Ebola Virus’s Co-Discoverer On India’s COVID-19 Crisis

Backed by the studies, Joe Biden’s top medical advisor also added that both the variants–B.1.617 and B.1.618 that have been identified in India– have been neutralised with both the vaccines. The US reported its first case of B.1.617, the variant that emerged in India, in early April. Stanford researchers found this variant in northern California. Since then, cases have been detected in Iowa, Nevada, and other states. Several of these cases are linked to international travel – causing the Biden administration to restrict travel from India.

Also Read: Bleeding, Clotting Cases After Covishield Jab “Minuscule”: Centre’s Panel

(This story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

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