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Pfizer, Moderna Vaccines May Greatly Reduce Risk Of Asymptomatic COVID-19 Infection, Study Says

The findings, published in the journal Clinical Infectious Diseases, underscore the efficacy of mRNA vaccines for Covid-19 to significantly limit the spread of Covid-19 by people with no symptoms who may unknowingly spread the infection to others

Pfizer, Moderna Vaccines May Greatly Reduce Risk Of Asymptomatic COVID-19 Infection, Study Says
Highlights
  • An mRNA vaccine is based on RNA of the novel coronavirus: Experts
  • Several vaccines are now clinically available under emergency use
  • Pfizer and Moderna are mRNA vaccines

Washington: Patients without COVID-19 symptoms are far less likely to test positive, and unknowingly spread COVID-19 ten days after receiving a second dose of a messenger RNA vaccine, compared to those who have not been vaccinated, a study says. Researchers from Mayo Clinic in the US noted that several vaccines are now clinically available under emergency use authorisation and have demonstrated efficacy against symptomatic COVID-19. However, the impact of vaccines on asymptomatic SARS-CoV-2 infection is largely unknown, they said.
The Pfizer-BioNTech and Moderna messenger RNA (mRNA) vaccines for COVID-19 are authorised for emergency use in many countries. An mRNA vaccine is based on the segments of the genetic material, or RNA, of the novel coronavirus.

Also Read: One Year After WHO Declared COVID-19 A Global Pandemic, The World Continues To Be Under The Threat Of Coronavirus Variants

With two doses of a mRNA COVID-19 vaccine, people with no symptoms showed an 80 per cent lower adjusted risk of testing positive for the disease after their last dose, according to the researchers. The findings, published in the journal Clinical Infectious Diseases, underscore the efficacy of mRNA vaccines for COVID-19 to significantly limit the spread of COVID-19 by people with no symptoms who may unknowingly spread the infection to others.

We found that those patients without symptoms receiving at least one dose of the first authorised mRNA COVID-19 vaccine, Pfizer-BioNTech, 10 days or more prior to screening were 72 per cent less likely to test positive. Those receiving two doses were 73 per cent less likely, compared to the unvaccinated group, said Aaron Tande, a Mayo Clinic infectious diseases specialist and co-first author of the paper.

After adjusting for a range of factors, researchers found an 80 per cent risk reduction of testing positive for COVID-19 among those with two doses of an mRNA COVID-19 vaccine. The researchers retrospectively looked at a cohort of 39,000 patients who underwent pre-procedural molecular screening tests for COVID-19.

Over 48,000 screening tests were performed, including 3,000 on patients who had received at least one dose of an mRNA COVID-19 vaccine, they said. According to the researchers, these screening tests were part of routine COVID-19 testing prior to treatments not related to COVID-19, such as surgeries and other procedures. Patients in the vaccinated group had received at least one dose of a messenger RNA COVID-19 vaccine, they added.

Also Read: COVID Vaccination: Experts Answer Queries Related To Coronavirus Vaccine And Comorbidities

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

26,78,24,983Cases
22,84,48,447Active
3,40,97,388Recovered
52,79,148Deaths
Coronavirus has spread to 196 countries. The total confirmed cases worldwide are 26,78,24,983 and 52,79,148 have died; 22,84,48,447 are active cases and 3,40,97,388 have recovered as on December 9, 2021 at 3:47 am.

India

3,46,66,241 9,419Cases
94,742 1,009Active
3,40,97,388 8,251Recovered
4,74,111 159Deaths
In India, there are 3,46,66,241 confirmed cases including 4,74,111 deaths. The number of active cases is 94,742 and 3,40,97,388 have recovered as on December 9, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

66,40,888 893

9,964 157

64,89,720 1,040

1,41,204 10

Kerala

51,78,892 5,038

41,615 887

50,95,263 4,039

42,014 112

Karnataka

29,99,098 399

7,284 155

29,53,565 238

38,249 6

Tamil Nadu

27,32,648 703

7,946 36

26,88,142 728

36,560 11

Andhra Pradesh

20,74,217 181

2,011 3

20,57,749 176

14,457 2

Uttar Pradesh

17,10,502 10

139 7

16,87,452 3

22,911

West Bengal

16,20,803 574

7,576 0

15,93,659 568

19,568 6

Delhi

14,41,514 65

404 28

14,16,010 36

25,100 1

Odisha

10,50,760 255

1,931 11

10,40,403 264

8,426 2

Chhattisgarh

10,07,075 37

341 9

9,93,140 27

13,594 1

Rajasthan

9,54,984 40

236 16

9,45,792 24

8,956

Gujarat

8,27,873 67

417 45

8,17,361 22

10,095

Madhya Pradesh

7,93,288 14

140 1

7,82,619 13

10,529

Haryana

7,71,904 29

223 15

7,61,626 14

10,055

Bihar

7,26,259 9

36 6

7,14,133 3

12,090

Telangana

6,77,546 205

3,871 19

6,69,673 185

4,002 1

Assam

6,18,042 134

2,541 24

6,09,374 158

6,127

Punjab

6,03,578 22

350 0

5,86,614 20

16,614 2

Jharkhand

3,49,383 16

129 7

3,44,113 23

5,141

Uttarakhand

3,44,402 17

192 3

3,36,799 14

7,411

Jammu And Kashmir

3,38,198 151

1,639 38

3,32,070 111

4,489 2

Himachal Pradesh

2,27,753 69

722 14

2,23,174 81

3,857 2

Goa

1,79,307 65

441 37

1,75,478 28

3,388

Mizoram

1,37,377 320

3,049 10

1,33,819 309

509 1

Puducherry

1,29,128 23

230 1

1,27,022 22

1,876

Manipur

1,25,429 23

325 5

1,23,119 28

1,985

Tripura

84,888 14

94 11

83,968 3

826

Meghalaya

84,631 12

240 11

82,916 23

1,475

Chandigarh

65,515 7

67 2

64,628 5

820

Arunachal Pradesh

55,298 3

29 2

54,989 5

280

Sikkim

32,390 8

200 2

31,785 6

405

Nagaland

32,143 1

116 2

31,328 3

699

Ladakh

21,749 14

230 17

21,304 31

215

Dadra And Nagar Haveli

10,683

0 0

10,679

4

Lakshadweep

10,405

11 0

10,343

51

Andaman And Nicobar Islands

7,691 1

3 0

7,559 1

129

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