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Six COVID-19 Vaccine Candidates In Different Clinical Trial Stage In India, Three In Pre-Clinical Stage: Union Health Secretary

According to Union Health Secretary Rajesh Bhushan, a total of around 97 lakh cases of COVID-19 have been reported in the country out of which there are less than 4 lakh active cases

Six COVID-19 Vaccine Candidates In Different Clinical Trial Stage In India, Three In Pre-Clinical Stage: Union Health Secretary
  • Even after vaccination, COVID-19 precautions must be followed: Centre
  • Serum Institute of India has applied for emergency approval for Covishield
  • As many as 14.80 crore COVID-19 tests have been conducted in the country

New Delhi: Union Health Secretary Rajesh Bhushan on Tuesday (December 8) said that there are six COVID-19 vaccine candidates in different clinical trial stages being developed by various manufacturers in India. Besides this, three COVID-19 vaccine candidates are in the pre-clinical stage of which one of the coronavirus vaccine candidates is in the pre-development stage being researched by Aurobindo Pharma, the official said. “Six vaccines are in the clinical trial stage. And there are three vaccines in the pre-clinical stage. Some of them may get licensed in the coming weeks but we cannot foretell at this moment of time because licensing is the domain of the national regulator the Drugs Controller General of India,” Mr. Bhushan said at a press conference organised by the Health Ministry here.

Also Read: Centre Develops ‘Co-WIN’ App To Self-Register For COVID-19 Vaccine

These vaccines are of two to three doses. Even after vaccination, COVID-19 precautions must be followed as advised by the scientists, he noted.

The first vaccine is Covishield, which is being manufactured on the Chimpanzee Adenovirus platform and by the Serum Institute of India (SII) in Pune. The collaborative company is AstraZeneca. “The regulator had allowed the phase 2 and 3 clubbed clinical trials of the vaccine to them and they have applied for emergency use authorisation,” he said.

On Covaxin, he said that this vaccine is on an inactivated virus platform.

This is being manufactured by Bharat Biotech International Limited, Hyderabad in collaboration with the Indian Council of Medical Research (ICMR). The vaccine is in phase 3 trials. They have also applied for emergency use authorisation.

The third vaccine candidate is ZyCoV-D which is based on the DNA platform. It is being manufactured by Cadila Healthcare Ltd, Ahmedabad. Their collaborator is the Department of Biotechnology. It is in phase 3 of the trials.
The Health Secretary further said that the fourth vaccine candidate is the Russian vaccine (Sputnik V) which is based on the human adenovirus platform. It is being manufactured by Dr Reddy’s lab in Hyderabad. Their collaborator is Gamaleya National Centre, Russia. Their phase 3 trial will begin next week.

The fifth vaccine candidate is NVX-CoV2373 which is based on the protein sub-unit platform. It is being developed by the Serum Institute of India, Pune. Their collaborator is Novavax and the phase 3 trial of this vaccine is under consideration in India.

Also Read: Elderly Couple Becomes First Indian-Origin Recipients Of Vaccine Against COVID-19 In United Kingdom

The sixth vaccine candidate is a recombinant protein antigen-based vaccine. It is being manufactured by Biological E Ltd, Hyderabad. Their collaborator is Massachusetts Institute of Technology, USA. The pre-clinical animal studies have concluded for this vaccine, he said.

The seventh vaccine candidate is HGCO 19 which is an mRNA-based vaccine. It is being manufactured by Genova, Pune. Their collaborator is HDT, USA. The pre-clinical animal studies are over for this vaccine. Phase 1 and 2 clinical trials will start for this vaccine in the near future.

The Health Secretary added that the eighth vaccine candidate is on an inactivated rabies vector platform.

It is being manufactured by the Bharat Biotech International Ltd, Hyderabad. Their collaborator is Thomas Jefferson University, USA. It is in the advanced pre-clinical trial stage. Vaccination efforts of the country are guided by the principles regarding the same espoused by Prime Minister Narendra Modi on August 15 from the ramparts of red fort, he added.

The Health Secretary further said that there are 3.83 lakh active cases in India as of Tuesday.

A total of around 97 lakh cases have been reported in the country out of which there are less than 4 lakh active cases. Active cases are those who are in hospitals or in self-isolation at their homes. There are 3.83 lakh active cases in the country. The total number of deaths reported due to COVID-19 stands at 1.40 lakhs. As many as 14.80 crore tests have been conducted in the country. India has 7,000 cases per million which is one of the lowest in the world, he informed.

Also Read: Bharat Biotech Seeks Emergency Use Authorisation For Indigenously Developed COVID-19 Vaccine Covaxin

Meanwhile, UK Prime Minister Boris Johnson today announced that the first vaccinations against the coronavirus have begun in the country. Taking to Twitter, Mr. Johnson said,

Today the first vaccinations in the UK against COVID-19 begin. Thank you to our NHS, to all of the scientists who worked so hard to develop this vaccine, to all the volunteers – and to everyone who has been following the rules to protect others. We will beat this together.

On December 2, the UK became the first country in the world to authorise the use of Pfizer and BioNTech for emergency purposes, thus, paving way for the delivery of the vaccines.

The first recipient of the vaccine was Margaret Keenan from Northern Ireland who is 90-year-old. She was vaccinated at University Hospital in Coventry earlier on Tuesday.

According to the latest data by the Johns Hopkins University, globally 67,650,207 people have tested positive for coronavirus and 1,545,723 deaths have been reported so far.

Also Read: Serum Institute Likely To Supply COVID Vaccine At Rs. 250 Per Dose: Report

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene


Coronavirus has spread to 196 countries. The total confirmed cases worldwide are 26,43,68,460 and 52,38,032 have died; 22,50,84,762 are active cases and 3,40,45,666 have recovered as on December 3, 2021 at 1:36 pm.


3,46,15,757 9,216Cases
99,976 213Active
3,40,45,666 8,612Recovered
4,70,115 391Deaths
In India, there are 3,46,15,757 confirmed cases including 4,70,115 deaths. The number of active cases is 99,976 and 3,40,45,666 have recovered as on December 3, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths

66,37,221 796

10,882 180

64,85,290 952

1,41,049 24


51,51,919 4,700

45,030 252

50,66,034 4,128

40,855 320


29,96,833 363

6,772 169

29,51,845 191

38,216 3

Tamil Nadu

27,28,350 715

8,155 45

26,83,691 748

36,504 12

Andhra Pradesh

20,73,252 159

2,138 11

20,56,670 169

14,444 1

Uttar Pradesh

17,10,417 12

93 1

16,87,413 11


West Bengal

16,17,408 657

7,690 22

15,90,208 667

19,510 12


14,41,190 217

307 21

14,15,785 196



10,49,597 252

2,211 26

10,38,971 276

8,415 2


10,06,870 37

328 12

9,92,949 25



9,54,827 21

213 10

9,45,659 11



8,27,570 50

318 25

8,17,158 24

10,094 1

Madhya Pradesh

7,93,199 12

128 4

7,82,543 8



7,71,760 27

178 9

7,61,528 18



7,26,230 5

32 0

7,16,534 4

9,664 1


6,76,376 189

3,680 50

6,68,701 137

3,995 2


6,17,163 124

2,535 77

6,08,517 198

6,111 3


6,03,352 32

344 13

5,86,402 18

16,606 1


3,49,271 15

95 1

3,44,035 13

5,141 1


3,44,325 22

182 4

3,36,735 18


Jammu And Kashmir

3,37,263 177

1,697 10

3,31,089 167


Himachal Pradesh

2,27,354 85

835 29

2,22,669 113

3,850 1


1,79,046 56

367 40

1,75,295 16



1,35,765 315

3,717 55

1,31,545 368

503 2


1,28,998 33

299 10

1,26,826 23



1,25,269 33

663 4

1,22,627 28

1,979 1


84,835 15

94 6

83,916 8

825 1


84,534 24

296 2

82,764 25

1,474 1


65,475 4

65 1

64,590 5


Arunachal Pradesh

55,285 6

36 1

54,969 5



32,267 15

137 10

31,727 5



32,128 3

128 5

31,302 6

698 2


21,642 41

306 21

21,122 20


Dadra And Nagar Haveli


0 1

10,679 1



10,397 1

18 8

10,328 9


Andaman And Nicobar Islands

7,686 3

7 2

7,550 1


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