Centre Issues Guidelines For Management Of Black Fungus Disease In Children Below 18 Years

Centre Issues Guidelines For Management Of Black Fungus Disease In Children Below 18 Years

As per the Ministry of Health and Family Welfare (MoHFW), Black Fungus or Mucormycosis is a serious fungal disease seen in patients with underlying or predisposing factors such as immunosuppression, poorly controlled diabetes mellitus, misuse or overuse of steroids, cancer, organ/stem cell transplantation, and those under prolonged ICU treatment
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Centre Issues Guidelines For Management Of Black Fungus Disease In Children Below 18 YearsBlack Fungus or Mucormycosis is being reported among COVID-19 patients lately
Highlights
  • Ministry of Health and Family Welfare has called mucormycosis an emergency
  • Do not wait for culture results to initiate therapy: Centre
  • In its guidelines, centre has explained dosage administration to children

New Delhi: The Director General of Health Services (DGHC) under the Union Health Ministry on Wednesday (June 9) issued guidelines for the management of Mucormycosis or black fungus disease in children below 18 years. As per the Ministry of Health and Family Welfare (MoHFW), Mucormycosis is a serious fungal disease seen in patients with underlying/predisposing factors such as immunosuppression, poorly controlled diabetes mellitus, misuse/overuse of steroids, cancer, organ/stem cell transplantation, and those under prolonged ICU treatment.

Also Read: Coronavirus Explained: What Is Mucormycosis Or Black Fungus And How It Affects COVID-19 Patients

Do not wait for culture results to initiate therapy as mucormycosis is an emergency. Early complete surgical debridement is the cornerstone of treatment, and maybe repeated as required, the DGHC said in its guideline.

According to the guidelines, “Conventional Amphotericin B as a prolonged IV infusion through a central venous catheter or PICC; closely monitor kidney function and electrolytes during treatment. Reconstitute in water for injection, and dilute in 5 per cent dextrose (do not use normal saline/Ringer’s lactate, start with test dose: 1 mg IV infusion over 20-30 minute. Loading dose: 0.25-0.5 mg/kg IV infused over 2-6 hours; gradually increase by 0.25 mg-increments/day to reach maintenance dose: 1-1.5 mg/kg/day.”

Liposomal Amphotericin B or Amphotericin lipid complex, if available; prolonged infusion over 2-3hours through a central venous catheter or PICC and closely monitoring KFT and electrolytes. Reconstitute in water for injection, and dilute in 5 per cent dextrose (do not use normal saline/Ringer’s lactate); start full dose from first day; 5 mg/kg/day (10 mg/kg/day in case of CNS involvement), it said.

“Posaconazole should be given as salvage therapy in cases who cannot be given Amphotericin B. Children less than 11 years in age dose – 7-12 mg/kg/dose IV twice on the first day and maintenance dose – 7-12 mg/kg IV once a day, starting on the second day,” it added.

Also Read: COVID Management In Children: Government Suggests Rational Use Of CT Scan, 6-Minute Walk Test, No Remdesivir

(This story has not been edited by NDTV staff and is published from a syndicated feed.)

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World

17,91,56,496Cases
5,81,68,051Active
11,71,06,212Recovered
38,82,233Deaths
Coronavirus has spread to 193 countries. The total confirmed cases worldwide are 17,91,56,496 and 38,82,233 have died; 5,81,68,051 are active cases and 11,71,06,212 have recovered as on June 23, 2021 at 3:45 am.

India

3,00,28,709 50,848Cases
6,43,19419,327Active
2,89,94,855 68,817Recovered
3,90,660 1,358Deaths
In India, there are 3,00,28,709 confirmed cases including 3,90,660 deaths. The number of active cases is 6,43,194 and 2,89,94,855 have recovered as on June 23, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

59,87,521 8,470

1,26,468 1,055

57,42,258 9,043

1,18,795 482

Kerala

28,29,460 12,617

1,00,881 746

27,16,284 11,730

12,295 141

Karnataka

28,15,029 3,709

1,18,615 4,541

26,62,250 8,111

34,164 139

Tamil Nadu

24,36,819 6,895

56,886 4,443

23,48,353 11,144

31,580 194

Andhra Pradesh

18,57,352 4,169

53,880 4,260

17,91,056 8,376

12,416 53

Uttar Pradesh

17,04,678 202

3,910 253

16,78,486 397

22,282 58

West Bengal

14,85,438 1,852

22,508 232

14,45,493 2,037

17,437 47

Delhi

14,32,778 397

1,918 78

14,05,927 467

24,933 8

Chhattisgarh

9,91,653 482

8,007 557

9,70,244 1,032

13,402 7

Rajasthan

9,51,393 137

2,388 303

9,40,101 437

8,904 3

Odisha

8,83,490 2,957

30,859 1,240

8,48,960 4,159

3,671 38

Gujarat

8,22,620 135

5,159 480

8,07,424 612

10,037 3

Madhya Pradesh

7,89,415 65

1,707 273

7,78,902 318

8,806 20

Haryana

7,67,726 146

2,200 137

7,56,231 263

9,295 20

Bihar

7,20,207 268

2,811 206

7,07,833 468

9,563 6

Telangana

6,15,574 1,175

16,640 606

5,95,348 1,771

3,586 10

Punjab

5,93,063 405

5,968 509

5,71,207 880

15,888 34

Assam

4,88,179 2,869

32,975 350

4,50,924 2,482

4,280 37

Jharkhand

3,44,775 110

1,417 72

3,38,256 180

5,102 2

Uttarakhand

3,38,978 171

2,896 68

3,29,030 231

7,052 8

Jammu And Kashmir

3,12,584 428

7,181 578

3,01,134 999

4,269 7

Himachal Pradesh

2,00,791 188

2,276 132

1,95,062 315

3,453 5

Goa

1,64,957 303

2,920 146

1,59,029 438

3,008 11

Puducherry

1,15,364 284

3,214 150

1,10,423 433

1,727 1

Manipur

64,993 575

9,214 84

54,714 649

1,065 10

Tripura

63,140 395

3,747 163

58,735 554

658 4

Chandigarh

61,467 23

278 33

60,383 56

806

Meghalaya

45,976 421

4,273 77

40,915 341

788 3

Arunachal Pradesh

33,664 289

2,548 9

30,956 279

160 1

Nagaland

24,438 64

1,757 87

22,204 149

477 2

Ladakh

19,871 33

360 5

19,309 38

202

Sikkim

19,458 137

2,430 18

16,732 152

296 3

Mizoram

18,409 430

4,424 197

13,900 233

85

Dadra And Nagar Haveli

10,520 4

61 1

10,455 3

4

Lakshadweep

9,504 33

315 4

9,142 36

47 1

Andaman And Nicobar Islands

7,425 10

103 6

7,195 4

127

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