Coronavirus Outbreak Explained: What Is mRNA COVID-19 Vaccine Technology Used By Pfizer-BioNTech And Moderna?

Coronavirus Outbreak Explained: What Is mRNA COVID-19 Vaccine Technology Used By Pfizer-BioNTech And Moderna?

Pfizer-BioNTech’s COVID-19 vaccine BNT162b2 and Moderna’s mRNA-1273 are mRNA (messenger-RNA) vaccines developed in the fight against COVID-19 pandemic
Coronavirus Outbreak Explained: What Is mRNA COVID-19 Vaccine Technology Used By Pfizer-BioNTech And Moderna?mRNA vaccines are called messenger RNA vaccines and are being used first time as part of the fight against COVID-19 pandemic
Highlights
  • mRNA vaccines are called messenger RNA vaccines
  • mRNA vaccines send a message to our cells to trigger an immune response
  • mRNA vaccines offer a strong immune response: Dr Parikh, Jaslok Hospital

New Delhi: Countries across the globe have started coronavirus vaccination programme in a fight against the COVID-19 disease caused by SARS-CoV-2. On December 11, 2020, the U.S. Food and Drug Administration issued the first emergency use authorisation to Pfizer-BioNTech’s COVID-19 vaccine for its use in the U.S. among individuals 16 years of age and older. Soon Pfizer-BioNTech’s COVID-19 was rolled out in the United Kingdom (U.K.), Canada and several mainland European countries. Other vaccine candidates like Oxford-AstraZeneca’s Covishield, Bharat Biotech’s Covaxin, Moderna’s COVID-19 vaccine among others have also got emergency use licenses in various countries. India too initiated its coronavirus vaccination drive from January 16 with restricted emergency use provided to Covishield and Covaxin. Though all vaccines aim at providing immunity from Novel Coronavirus, they are developed differently. For example, Pfizer-BioNTech’s BNT162b2 and Moderna’s mRNA-1273 use the genetic approach and have developed mRNA (messenger-RNA) vaccines. But what is an mRNA vaccine? NDTV spoke to experts to find out an answer.

Also Read: India’s Coronavirus Vaccination Drive: Union Health Minister Dispel Myths Surrounding COVID-19 Vaccine

What Are mRNA Vaccines And How Do They Work?

To trigger an immune response, many vaccines put a weakened or inactivated germ into our bodies but mRNA vaccines do not work like that. Explaining mRNA vaccines, Dr Rajesh Parikh, Director, Medical Research at Jaslok Hospital and the author of ‘The Vaccine Book for COVID-19’, said,

mRNA Vaccines are in the category of, ‘Subunit, recombinant, polysaccharide, and conjugate vaccines’. These vaccines use specific parts of the infectious agent like its protein, sugar, or coating.

As the name suggests, mRNA or messenger-RNA vaccine gives a message to our cells to make a protein or even just a piece of a protein which are like those of the SARS-CoV-2 virus. The protein then triggers an immune response inside our bodies. That immune response, which produces antibodies, is what protects us from getting infected if the real virus enters our bodies.

Also Read: NITI Aayog Member Dr VK Paul Answers Your Queries On COVID-19 Vaccination Drive To Be Launched By PM Modi

Further talking about mRNA vaccines, Dr Parikh said,

Because these vaccines use very specific regions, they offer a strong immune response targeting specific regions of the infective agent. They can be used on almost everyone, including those with compromised immunity.

Elaborating more on the immunity provided by mRNA vaccines, Dr Harsh Mahajan, Founder Of Mahajan Imaging and Chairman of CARINGdx, said, as part of its immune response, a human body produces T-cells and B-cells along with antibodies. He said,

T-cells and B-cells are called memory cells and they can retain the memory of infection for life; even after antibodies have faded. Since the memory cells remember the infection, they can trigger a faster and stronger immune response if the body catches the virus. However, in the case of the COVID-19, we don’t know for how long these cells retain memory.

Also Read: Will We Have A Choice For COVID-19 Vaccine? Does People Who Have Contracted COVID In Past Need To Get Vaccinated? An Expert Explains It All

How Are mRNA Vaccines Different From Oxford-AstraZeneca’s Covishield And Bharat Biotech’s Covaxin?

The Coronavirus vaccine developed by Oxford-AstraZeneca is called ChAdOx1 nCoV-19 or AZD1222 or Covishield in India. It is a viral vector vaccine; such vaccines use a safe virus to deliver specific sub-parts called proteins so that it can trigger an immune response without causing disease. The ChAdOx1 vaccine uses a chimpanzee adenovirus vaccine vector that usually causes the common cold in chimpanzees and does not infect humans.

The adenovirus has been weakened to an extent where it becomes incapable of causing an infection. When a vaccine is injected, it creates antigenic reaction and antibodies are formed and immune response of the host comes in, explained Dr Mahajan.

On the other hand, Bharat Biotech’s Covaxin is an inactivated vaccine. As part of the process, disease carrying virus, in the case of COVID-19 it is SARS-CoV-2, is inactivated or killed and then injected.

Inactivated vaccines have been around for ages and one example is polio vaccine, said Dr Mahajan.

Also Read: Oxford COVID-19 Vaccine Candidate Shows 70 Per Cent Efficacy Based On Data Of 11,636 Volunteers

How Are mRNA Vaccines Developed?

Dr Mahajan informed that mRNA vaccines are manufactured in a completely synthetic manner. As per the United States’ Centers for Disease Control and Prevention (CDC), since mRNA vaccines do not use the live virus that causes COVID-19, they cannot give someone COVID-19.

How Safe And Efficacious Are mRNA Vaccines?

mRNA vaccines being produced by Pfizer-BioNTech and Moderna have undergone the same set of clinical trials as other COVID-19 vaccine candidates. Trial results and efficacy analysis demonstrates Pfizer’s BNT162b2 to be 95 per cent effective against COVID-19. Moderna’s COVID-19 vaccine is also claimed to be 94.1 per cent effective.

On December 31, the World Health Organisation (WHO) listed the COVID-19 mRNA vaccine for emergency use, making the Pfizer-BioNTech vaccine the first to receive emergency validation from WHO since the outbreak began a year ago.

Regulatory experts convened by WHO from around the world and WHO’s own teams reviewed the data on the Pfizer-BioNTech vaccine’s safety, efficacy and quality as part of a risk-versus-benefit analysis. The review found that the vaccine met the must-have criteria for safety and efficacy set out by WHO, and that the benefits of using the vaccine to address COVID-19 offset potential risks, reads an official statement from WHO.

Also Read: COVID-19 Outbreak Explained: Can COVID-19 Vaccines Fight Against Virus Mutations?

How Many Shots Of mRNA Vaccines Are Required?

Currently, both available mRNA vaccines are two dose vaccines. The second shot is given three to four weeks from the first shot. The first shot gives some immunity; the second shot is a booster dose. According to the experts, it is important to stick to the vaccine schedule.

Do mRNA Vaccines Have Any Side-effect?

Most common side effects that an individual might witness after taking any vaccine are pain, swelling and redness in the arm where the shot is given. A person may also get chills, tiredness and headache. This is the reason, it is recommended to stay put at the vaccination centre for at least half-hour after vaccine inoculation.

mRNA vaccines have slightly more side effects as compared to live attenuated or killed virus vaccines. Significant allergic reactions were reported among two nurses in the U.K. who took Pfizer vaccine shot. These might be sporadic incidence. Generally, severe reactions show within half an hour of taking the shot and they can cause death, alerted Dr Mahajan.

Also Read: COVID-19 Outbreak Explained: What Do We Know So Far About The New Coronavirus Strains Detected In The United Kingdom And South Africa

What Are The Pros And Cons Of mRNA Vaccines?

According to Dr Parikh, mRNA is a novel technology and it’s very safe and efficacious. Adding to this, Dr Mahajan said, since mRNA vaccines are developed in a synthetic manner, there is no limitation to the number of vaccines we can manufacture. Further talking about the disadvantages, Dr Mahajan said,

Currently, these vaccines are expensive. Secondly, they need to be stored at an extremely cold temperature like Pfizer’s vaccine requires ultra-cold chain and need to be preserved at -70 degrees Celsius. Similarly, Moderna’s vaccine needs -25°C and -15°C temperature.

According to the CDC, Moderna’s vaccine vials may be stored in the refrigerator between 2°C and 8°C for up to 30 days.

Dr Ravindra M Mehta, Senior Consultant and HOD – Pulmonology and Interventional pulmonology, Apollo Speciality Hospitals Jayanagar, noted that since the technology is being used for the first time, there is a lack of knowledge. He said,

Surprisingly, vaccines are offering over 90 per cent efficacy but there is not much data on their long-term impact. The major advantages of mRNA vaccines are not very clear right now.

Also Read: Coronavirus Outbreak Explained: What Are Mild Symptoms Of COVID-19?

Do mRNA Vaccines Alter Host’s DNA?

According to the experts NDTV spoke to and CDC, mRNA never enters the nucleus of the cell, which is where our DNA (genetic material) is kept. In fact, the cell breaks down and gets rid of the mRNA soon after it is finished using the instructions.

Do We Have mRNA Vaccines For Any Other Disease?

According to the WHO, the nucleic acid approach that delivers a specific set of instructions to our cells is a new way of developing vaccines. Before the COVID-19 pandemic, none had yet been through the full approvals process for use in humans, though some DNA vaccines, including for particular cancers, were undergoing human trials, reads the WHO’s explainer on vaccine development and distribution.

mRNA vaccines have been studied before for influenza, rabies, Zika and cytomegalovirus. Besides mRNA technology has been used in cancer research to trigger immune responses to cancer cells, explained Dr Parikh.

Essentially, the technology has been there but it is the first time a vaccine based on mRNA has been produced and is being used.

Also Read: COVID-19 Pandemic Explained: What Is Reproduction (R) Number And Why Does It Matter?

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

11,29,83,901Cases
4,67,54,489Active
6,37,22,948Recovered
25,06,464Deaths
Coronavirus has spread to 192 countries. The total confirmed cases worldwide are 11,29,83,901 and 25,06,464 have died; 4,67,54,489 are active cases and 6,37,22,948 have recovered as on February 26, 2021 at 3:39 am.

India

1,10,63,491 16577Cases
1,55,986 4278Active
1,07,50,680 12179Recovered
1,56,825 120Deaths
In India, there are 1,10,63,491 confirmed cases including 1,56,825 deaths. The number of active cases is 1,55,986 and 1,07,50,680 have recovered as on February 26, 2021 at 2:30 am.

State & District Details

State Cases Active Recovered Deaths
DistrictCases
Mumbai45,478
Thane13,660
Pune9,920
Mumbai Suburban5,363
Aurangabad1,974
Nashik1,575
Raigad1,462
Palghar1,421
Solapur1,291
Jalgaon1,039
Akola757
Nagpur692
Kolhapur646
Satara629
Ratnagiri350
Amravati291
Dhule228
Hingoli208
Jalna201
Ahmednagar190
Nanded176
Yavatmal150
Sangli145
Latur139
Osmanabad125
Sindhudurg114
Buldhana88
Parbhani78
gondia69
Beed54
Nandurbar42
Gadchiroli42
Bhandara41
Chandrapur32
Washim13
Wardha11

21,29,821 8,702

65,461 4,902

20,12,367 3,744

51,993 56

DistrictCases
Kannur357
Kasaragod333
Palakkad224
Malappuram119
Kollam118
Thrissur106
Thiruvananthapuram104
Pathanamthitta98
Kozhikode90
Alappuzha76
Kottayam73
Ernakulam60
Idukki40
Wayanad36

10,48,686 3,677

52,164 989

9,92,372 4,652

4,150 14

DistrictCases
Udupi1,176
Kalaburagi669
Yadgir538
Bengaluru Urban529
Raichur369
Mandya346
Belagavi337
Bidar219
Hassan205
Davangere204
Vijayapura201
Dakshina Kannada179
Chikkaballapura149
Mysuru107
Bagalkote103
Uttara Kannada95
Shivamogga67
Dharwad61
Ballari60
Gadag45
Bengaluru Rural40
Tumakuru36
Kolar29
Haveri24
Chikkamagaluru19
Chitradurga14
Koppal5
Kodagu4
Ramanagara3
Chamarajanagara0

9,49,636 453

5,595 501

9,31,725 947

12,316 7

DistrictCases
Kurnool795
Krishna557
Guntur511
Anantapur428
East Godavari356
Chittoor319
Sri Potti Sriramulu Nell*296
Y.S.R.205
West Godavari199
Srikakulam183
Prakasam104
Visakhapatnam103
Vizianagaram23

8,89,585 82

611 8

8,81,806 74

7,168

DistrictCases
Chennai23,324
Chengalpattu1,314
Thiruvallur774
Villupuram509
Kanchipuram503
Tiruvannamalai496
Cuddalore477
Ariyalur444
Tirunelveli433
Tuticorin333
Kallakurichi324
Madurai322
Salem258
Coimbatore188
Virudhunagar185
Dindigul175
Perambalur133
Ranipet133
Thanjavur130
Theni129
Tiruchirappalli119
Ramanathapuram119
Tiruppur116
Kanniyakumari110
Tenkasi103
Nagapattinam99
Karur88
Namakkal83
Erode75
Vellore71
Thiruvarur67
Pudukkottai53
Sivaganga46
Tirupathur45
Krishnagiri43
The Nilgiris17
Dharmapuri15

8,50,096 467

4,053 9

8,33,560 471

12,483 5

DistrictCases
North West5,463
Central4,817
West4,768
New Delhi3,405
North3,059
East2,472
South East2,446
South West2,391
South2,329
North East1,914
Shahdara1,580

6,38,593 220

1,169 32

6,26,519 188

10,905

DistrictCases
Gautam Buddha Nagar1,119
Agra933
Ghaziabad794
Meerut504
Lucknow386
Saharanpur298
Kanpur Nagar286
Moradabad252
Varanasi243
Hapur225
Aligarh215
Basti214
Amethi206
Rampur203
Jaunpur194
Firozabad190
Barabanki168
Gorakhpur166
Bulandshahr166
Siddharth Nagar159
Ghazipur159
Bijnor157
Deoria143
Azamgarh138
Sant Kabeer Nagar132
Mathura129
Ayodhya120
Muzaffarnagar117
Sambhal116
Sultanpur97
Ambedkar Nagar92
Maharajganj85
Amroha80
Rae Bareli78
Bahraich73
Kheri72
Kannauj69
Baghpat68
Kushi Nagar67
Bhadohi60
Ballia60
Gonda59
Etah52
Hardoi49
Balrampur49
Mau48
Mainpuri46
Etawah46
Hathras43
Unnao42
Jalaun41
Jhansi41
Shamli40
Chandauli38
Auraiya37
Farrukhabad36
Sitapur32
Prayagraj30
Banda27
Shahjahanpur25
Shravasti23
Budaun23
Mirzapur22
Bareilly17
Kasganj16
Pratapgarh15
Pilibhit15
Sonbhadra10
Kaushambi6
Kanpur Dehat4
Chitrakoot4
Lalitpur3
Hamirpur3
Mahoba3
Fatehpur3

6,03,232 129

2,182 8

5,92,327 135

8,723 2

DistrictCases
Kolkata2,777
Howrah1,435
24 Paraganas North1,031
Hooghly604
24 Paraganas South281
Maldah235
Dinajpur Uttar216
Coochbehar210
Birbhum206
Medinipur West159
Medinipur East153
Nadia139
Purba Bardhaman130
Murshidabad125
Bankura116
Darjeeling97
Jalpaiguri88
Paschim Bardhaman70
Purulia66
Dinajpur Dakshin50
Alipurduar39
Kalimpong18
Jhargram9

5,74,500 199

3,353 24

5,60,887 219

10,260 4

DistrictCases
Ganjam581
Jajapur322
Khordha238
Baleshwar190
Kendrapara164
Cuttack155
Bhadrak137
Balangir129
Puri103
Sundargarh102
Jagatsinghapur91
Nayagarh86
Mayurbhanj73
Nuapada69
Gajapati61
Dhenkanal36
Boudh34
Kendujhar34
Deogarh33
Kalahandi33
Sonepur29
Kandhamal28
Anugul26
Malkangiri20
Bargarh16
Koraput16
Sambalpur16
Jharsuguda8
Nabarangpur2
Rayagada2

3,36,924 89

609 21

3,34,400 67

1,915 1

DistrictCases
Jaipur2,177
Jodhpur1,748
Udaipur724
Bharatpur563
Kota503
Nagaur500
Ajmer379
Dungarpur374
Pali352
Jhalawar329
Bhilwara250
Sikar231
Chittorgarh188
Tonk171
Jalore164
Rajsamand140
Sirohi130
Bikaner112
Banswara91
Alwar90
Churu81
Jhunjhunu64
Dausa61
Dholpur60
Baran59
Jaisalmer53
Barmer34
Hanumangarh31
SawaiMadhopur26
Karauli17
Pratapgarh14
Ganganagar8
Bundi5

3,19,929 128

1,208 4

3,15,936 124

2,785

DistrictCases
Bilaspur100
Korba100
Mungeli87
Baloda Bazar85
Jashpur77
Janjgir-Champa56
Mahasamund54
Rajnandgaon52
Kabirdham52
Raigarh47
Raipur46
Balod41
Korea39
Durg31
Bemetara21
Kanker19
Balrampur17
Surguja14
Gariyaband10
Surajpur9
Dhamtari6
Bijapur2
Bastar2
Dantewada0
Kondagaon0
Narayanpur0
Sukma0

3,11,900 220

2,865 46

3,05,214 258

3,821 8

DistrictCases
Hyderabad2,475
Ranga Reddy183
Suryapet87
Jagitial77
Nizamabad76
MedchalMalkajgiri75
Mancherial43
YadadriBhuvanagiri40
Jogulamba Gadwal40
Vikarabad40
Nalgonda33
Warangal Urban32
Mahabubnagar30
Sangareddy26
Khammam26
Adilabad22
Nirmal21
Karimnagar17
RajannaSircilla16
Medak11
Kamareddy11
Mahabubabad10
Jayashankar Bhupalapally9
Nagarkurnool8
Kumuram Bheem Asifabad8
Jangoan8
Siddipet7
Peddapalli5
Bhadradri Kothagudem5
Warangal Rural4
Mulugu3
Narayanpet3
Wanaparthy1

2,98,453 189

1,910 58

2,94,911 129

1,632 2

DistrictCases
Gurugram2,950
Faridabad867
Sonipat404
Rohtak145
Palwal120
Jhajjar114
Karnal104
Hisar98
Ambala93
Panipat78
Nuh68
Bhiwani60
Rewari56
Kurukshetra55
Sirsa50
Kaithal48
Mahendragarh47
CharkiDadri43
Panchkula39
Fatehabad38
Jind38
Yamunanagar19

2,70,263 166

1,054 99

2,66,166 67

3,043

DistrictCases
Ahmadabad17,125
Surat2,311
Vadodara1,555
Gandhinagar410
Mahesana159
Banas Kantha147
Bhavnagar146
Rajkot135
Arvalli134
Mahisagar125
Anand107
PanchMahals107
Patan105
SabarKantha101
Kachchh99
Kheda98
Jamnagar63
Bharuch56
Botad55
Surendranagar55
Valsad47
GirSomnath45
Dohad43
Chhotaudepur37
Naysari35
Junagadh31
Narmada25
DevbhumiDwarka22
Amreli16
Porbandar11
Tapi6
Dang5
Morbi4

2,68,571 424

1,991 122

2,62,172 301

4,408 1

DistrictCases
Patna279
Bhagalpur266
Rohtas256
Khagaria253
Begusarai243
Madhubani199
Munger188
Jehanabad178
Katihar175
Darbhanga143
Samastipur139
Siwan139
PurbiChamparan138
Purnia135
Banka134
Buxar134
Nalanda123
Gopalganj123
Nawada122
Sheikhpura118
Gaya115
Kaimur (bhabua)105
Bhojpur103
Saran101
Muzaffarpur96
Saharsa88
Supaul87
Vaishali87
Madhepura82
Kishanganj75
Aurangabad75
Sitamarhi73
Lakhisarai72
Araria68
Pashchim Champaran57
Arwal52
Jamui47
Sheohar20

2,62,418 61

478 31

2,60,401 91

1,539 1

DistrictCases
Indore3,839
Bhopal1,880
Ujjain799
Burhanpur351
Neemuch319
Jabalpur276
East Nimar266
Sagar228
Gwalior211
Khargone196
Dewas140
Dhar132
Mandsaur112
Morena109
Bhind87
Raisen71
Barwani60
Ratlam51
Rewa39
Shajapur39
Hoshangabad37
Vidisha37
Chhatarpur35
Betul35
Rajgarh31
Dindori29
Sheopur26
Damoh26
Satna24
Anuppur22
Panna20
Tikamgarh18
Sidhi17
Narsinghpur17
Chhindwara16
Agar Malwa15
Mandla15
Shivpuri15
Jhabua14
Shandol14
Singrauli13
Ashoknagar13
Datia12
Sehore12
Umaria10
Balaghat9
Guna8
Harda4
Alirajpur3
Katni3
Seoni2
Niwari0

2,60,681 368

2,435 165

2,54,387 201

3,859 2

DistrictCases
Kamrup Metro276
Golaghat203
Nagaon143
Hojai89
Dima Hasao86
Karimganj85
Tinsukia84
Cachar80
Dibrugarh61
Hailakandi57
Lakhimpur57
Marigaon50
Dhemaji47
Kamrup42
Kokrajhar37
Dhubri30
Charaideo29
Barpeta28
Udalguri28
Sonitpur27
Jorhat24
Nalbari23
Darrang20
Sivasagar20
Goalpara19
Biswanath16
Baksa14
KarbiAnglong13
Bongaigaon12
Chirang6
West KarbiAnglong5
South SalmaraMancachar4
Majuli2

2,17,484 30

1,623 17

2,14,770 13

1,091

DistrictCases
Amritsar485
Jalandhar297
Ludhiana293
Tarn Taran163
Gurdaspur154
Hoshiarpur140
S.A.S Nagar137
Patiala132
Sangrur107
Shahid Bhagat Singh Nagar (Nawanshahr)99
Pathankot86
Rupnagar (Ropar)74
Faridkot74
Sri Muktsar Sahib71
Moga65
Bathinda60
Fatehgarh Sahib57
Fazilka53
Firozepur50
Kapurthala44
Mansa31
Barnala25

1,80,382 563

3,870 272

1,70,713 278

5,799 13

DistrictCases
Anantnag395
Srinagar300
Kulgam295
Baramulla271
Shopian255
Kupwara231
Bandipora175
Udhampur155
Ramban151
Jammu138
Budgam110
Pulwama108
Kathua53
Rajouri39
Ganderbal37
Poonch35
Doda27
Reasi26
Samba25
Kishtwar10
Mirpur0
Muzaffarabad0

1,26,201 108

820 49

1,23,426 59

1,955

DistrictCases
East Singhbum170
Ranchi148
Hazaribagh110
Garhwa80
Ramgarh75
Koderma58
Simdega48
Dhanbad32
Gumla28
Palamu27
West Singhbhum21
SaraikelaKharsawan20
Giridih19
Bokaro16
Latehar14
Khunti10
Lohardaga8
Deoghar5
Dumka5
Pakur4
Jamtara2
Godda2
Chatra1
Sahebganj0

1,19,795 76

467 36

1,18,241 40

1,087

DistrictCases
Dehradun370
Nainital323
Tehri Garhwal110
Haridwar94
Udam Singh Nagar83
Almora71
Champawat45
Pithoragarh43
Chamoli36
PauriGarhwal36
Bageshwar31
Rudraprayag30
Uttar Kashi24

97,031

491 0

94,850

1,690

DistrictCases
Hamirpur117
Kangra105
Una41
Solan32
Chamba29
Bilaspur21
Mandi21
Sirmaur11
Shimla10
Kullu4
Kinnaur2
Lahaul And Spiti0

58,499 42

244 15

57,260 27

995

DistrictCases
South Goa69
North Goa57

54,771 71

531 36

53,449 33

791 2

DistrictCases
Pondicherry111
Mahe4
Karaikal2
Yanam0

39,677 21

196 7

38,814 13

667 1

DistrictCases
Dhalai196
Sepahijala174
Gomati74
South Tripura53
Unakoti49
West Tripura45
Khowai24
North Tripura14

33,407 7

32 7

32,984

391

DistrictCases
Churachandpur32
Kangpokpi26
Imphal West21
Thoubal18
Imphal East10
Tengnoupal9
Bishnupur7
Senapati6
Chandel5
Kamjong5
Ukhrul4
Jiribam3
Pherzawl3
Kakching2
Tamenglong2
Noney1

29,253 3

40 1

28,840 4

373

DistrictCases
Chandigarh313

21,590 49

279 29

20,960 20

351

DistrictCases
Changlang31
Papum Pare8
Lohit3
Namsai2
West Siang1
East Siang1
Upper Siang1
Tawang1
PakkeKessang1
West Kameng0
Upper Subansiri0
Tirap0
Siang0
Shi Yomi0
Anjaw0
Lower Subansiri0
Lower Dibang Valley0
Longding0
Leparada0
KurungKumey0
KraDaadi0
Kamle0
East Kameng0
Dibang Valley0
Lower Siang0

16,836

3 1

16,777 1

56

DistrictCases
East Khasi Hills22
West Garo Hills5
South West Garo Hills4
North Garo Hills1
West Jaintia Hills1
West Khasi Hills1
East Garo Hills0
East Jaintia Hills0
Ribhoi0
South Garo Hills0
South West Khasi Hills0

13,961 3

20 2

13,793 1

148

DistrictCases
Dimapur20
Mon8
Kohima7
Kiphire3
Tuensang3
Peren2
Phek1
Longleng0
Mokokchung0
Wokha0
Zunheboto0

12,198 6

13 5

12,094 1

91

DistrictCases
Kargil77
LehLadakh43

9,814 7

56 3

9,628 4

130

DistrictCases
East District3
South District3
North District0
West District0

6,133 1

43 4

5,955 5

135

DistrictCases
South Andamans33
Nicobars1
North And Middle Andaman1

5,016

2 2

4,952 2

62

DistrictCases
Kolasib11
Aizawl10
Mamit8
Lawngtlai2
Lunglei2
Saitual1
Champhai0
Hnahthial0
Khawzawl0
Saiha0
Serchhip0

4,419 6

27 4

4,382 2

10

DistrictCases
Dadra And Nagar Haveli20

3,405 1

5 1

3,398

2

DistrictCases
Lakshadweep District0

331 9

86 0

244 8

1 1

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