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COVID Antibodies Are Transferred From Pregnant Women To Their Babies

According to a new study, pregnant women who generate protective antibodies after contracting the coronavirus often convey some of that natural immunity to their fetuses

COVID Antibodies Are Transferred From Pregnant Women To Their Babies
Highlights
  • All women who were studied had COVID-19 antibodies in their blood: Expert
  • Antibodies were high in symptomatic women among the sample: Study
  • Pregnant women have same immune response to COVD-19 as others: Study

Washington: The findings of a recent study suggested that antibodies that help in guarding against the COVID-19 virus are transferred from mothers to their babies while in the womb. This discovery, published in the ‘American Journal of Obstetrics and Gynecology’, adds to growing evidence that suggests that pregnant women who generate protective antibodies after contracting the coronavirus often convey some of that natural immunity to their fetuses.

Also Read: Role Of Private Sector In COVID-19 Vaccination To Get Deeper And Wider Soon: NITI Aayog Member

The findings also lend support to the idea that vaccinating mothers-to-be may also have benefits for their newborns.

Since we can now say that the antibodies pregnant women make against COVID-19 have been shown to be passed down to their babies, we suspect that there’s a good chance they could pass down the antibodies the body makes after being vaccinated as well, said Dr Yawei Jenny Yang, an assistant professor of pathology and laboratory medicine at Weill Cornell Medicine and the study’s senior author.

Dr Yang and her team analysed blood samples from 88 women who gave birth at New York-Presbyterian/Weill Cornell Medical Center between March and May 2020, a time when New York City was the global epicentre of the pandemic. All of the women had COVID-19 antibodies in their blood, indicating that they had contracted the virus at some point even though 58 per cent of those women had no symptoms.

Furthermore, while antibodies were detected in both symptomatic and asymptomatic women, the researchers observed that the concentration of antibodies was significantly higher in symptomatic women.

They also found that the general pattern of antibody response was similar to the response seen in other patients, confirming that pregnant women have the same kind of immune response to the virus as the larger patient population–something that hadn’t previously been known for sure since a woman’s immune system changes throughout pregnancy.

Also Read: Maharashtra Government Announces Week-Long Lockdown In Amravati Amid Rising COVID-19 Cases

In addition, the vast majority of the babies born to these women–78 per cent–had detectable antibodies in their umbilical cord blood. There was no evidence that any of the infants had been directly infected with the virus and all were COVID negative at the time of birth, further indicating that the antibodies had crossed the placenta–the organ that provides oxygen and nutrients to a growing baby during pregnancy–into the fetal bloodstream.

Newborns with symptomatic mothers also had higher antibody levels than those whose mothers had no COVID symptoms. This data implies that pregnant women could pass along vaccine-generated antibodies in the same way, potentially shielding both mother and child from future infection.

However, it is not yet known exactly how protective these antibodies might be, or how long that protection might last. Dr Laura Riley, chair of the Department of Obstetrics and Gynecology at Weill Cornell Medicine, obstetrician and gynaecologist-in-chief at NewYork-Presbyterian/Weill Cornell, and one of the study’s co-authors, is still advising pregnant patients who decide to get vaccinated to continue to follow current safety guidelines to prevent the spread of the disease.

Dr Riley, Dr Yang, and their colleagues are leading follow-up investigations that are currently enrolling pregnant women who receive the vaccine, as well as vaccinated mothers who are breastfeeding, to assess the antibody response in those groups after vaccination. That information could help guide maternal vaccination strategies moving forward.

The USD 1 million question is: Will the group of women who are now being vaccinated get the same type of protection? We don’t know that yet. Getting those answers is going to be really important, Dr Riley said.

Also Read: COVID-19 Variant N440K Spreading More In Southern States: Centre For Cellular And Molecular Biology

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

24,50,12,529Cases
20,64,25,824Active
3,36,14,434Recovered
49,72,271Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 24,50,12,529 and 49,72,271 have died; 20,64,25,824 are active cases and 3,36,14,434 have recovered as on October 28, 2021 at 4:00 am.

India

3,42,31,809 16,156Cases
1,60,9891,672Active
3,36,14,434 17,095Recovered
4,56,386 733Deaths
In India, there are 3,42,31,809 confirmed cases including 4,56,386 deaths. The number of active cases is 1,60,989 and 3,36,14,434 have recovered as on October 28, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

66,06,536 1,485

23,096 3,500

64,43,342 4,947

1,40,098 38

Kerala

49,38,603 9,445

77,158 2,100

48,31,468 6,723

29,977 622

Karnataka

29,86,835 282

8,459 80

29,40,339 349

38,037 13

Tamil Nadu

26,98,493 1,075

12,288 252

26,50,145 1,315

36,060 12

Andhra Pradesh

20,64,854 567

4,777 122

20,45,713 437

14,364 8

Uttar Pradesh

17,10,114 13

100 6

16,87,115 7

22,899

West Bengal

15,89,042 976

7,973 124

15,61,973 837

19,096 15

Delhi

14,39,709 38

348 25

14,14,270 13

25,091

Odisha

10,39,818 549

4,392 213

10,27,108 334

8,318 2

Chhattisgarh

10,05,926 28

263 14

9,92,088 12

13,575 2

Rajasthan

9,54,411 4

20 0

9,45,437 4

8,954

Gujarat

8,26,481 17

173 2

8,16,220 15

10,088

Madhya Pradesh

7,92,804 20

108 9

7,82,172 10

10,524 1

Haryana

7,71,204 15

133 5

7,61,022 10

10,049

Bihar

7,26,073 5

41 1

7,16,371 4

9,661

Telangana

6,70,829 186

4,164 63

6,62,714 122

3,951 1

Assam

6,09,506 244

3,838 153

5,99,681 391

5,987 6

Punjab

6,02,289 38

246 20

5,85,487 16

16,556 2

Jharkhand

3,48,705 28

160 30

3,43,408 56

5,137 2

Uttarakhand

3,43,861 17

150 6

3,36,312 23

7,399

Jammu And Kashmir

3,31,865 70

838 16

3,26,596 86

4,431

Himachal Pradesh

2,23,406 261

1,972 211

2,17,693 48

3,741 2

Goa

1,77,969 23

454 29

1,74,152 51

3,363 1

Puducherry

1,27,846 40

443 10

1,25,546 50

1,857

Manipur

1,23,473 70

844 29

1,20,712 97

1,917 2

Mizoram

1,19,496 547

7,320 446

1,11,752 991

424 2

Tripura

84,438 15

123 1

83,499 14

816

Meghalaya

83,466 51

507 22

81,511 71

1,448 2

Chandigarh

65,331 5

29 2

64,482 3

820

Arunachal Pradesh

55,120 6

115 22

54,725 28

280

Sikkim

31,925 13

177 1

31,353 12

395

Nagaland

31,759 12

222 3

30,856 15

681

Ladakh

20,925 8

47 6

20,670 2

208

Dadra And Nagar Haveli

10,682 1

6 0

10,672 1

4

Lakshadweep

10,365

0 0

10,314

51

Andaman And Nicobar Islands

7,650 2

5 1

7,516 1

129

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