- All women who were studied had COVID-19 antibodies in their blood: Expert
- Antibodies were high in symptomatic women among the sample: Study
- Pregnant women have same immune response to COVD-19 as others: Study
Washington: The findings of a recent study suggested that antibodies that help in guarding against the COVID-19 virus are transferred from mothers to their babies while in the womb. This discovery, published in the ‘American Journal of Obstetrics and Gynecology’, adds to growing evidence that suggests that pregnant women who generate protective antibodies after contracting the coronavirus often convey some of that natural immunity to their fetuses.
The findings also lend support to the idea that vaccinating mothers-to-be may also have benefits for their newborns.
Since we can now say that the antibodies pregnant women make against COVID-19 have been shown to be passed down to their babies, we suspect that there’s a good chance they could pass down the antibodies the body makes after being vaccinated as well, said Dr Yawei Jenny Yang, an assistant professor of pathology and laboratory medicine at Weill Cornell Medicine and the study’s senior author.
Dr Yang and her team analysed blood samples from 88 women who gave birth at New York-Presbyterian/Weill Cornell Medical Center between March and May 2020, a time when New York City was the global epicentre of the pandemic. All of the women had COVID-19 antibodies in their blood, indicating that they had contracted the virus at some point even though 58 per cent of those women had no symptoms.
Furthermore, while antibodies were detected in both symptomatic and asymptomatic women, the researchers observed that the concentration of antibodies was significantly higher in symptomatic women.
They also found that the general pattern of antibody response was similar to the response seen in other patients, confirming that pregnant women have the same kind of immune response to the virus as the larger patient population–something that hadn’t previously been known for sure since a woman’s immune system changes throughout pregnancy.
In addition, the vast majority of the babies born to these women–78 per cent–had detectable antibodies in their umbilical cord blood. There was no evidence that any of the infants had been directly infected with the virus and all were COVID negative at the time of birth, further indicating that the antibodies had crossed the placenta–the organ that provides oxygen and nutrients to a growing baby during pregnancy–into the fetal bloodstream.
Newborns with symptomatic mothers also had higher antibody levels than those whose mothers had no COVID symptoms. This data implies that pregnant women could pass along vaccine-generated antibodies in the same way, potentially shielding both mother and child from future infection.
However, it is not yet known exactly how protective these antibodies might be, or how long that protection might last. Dr Laura Riley, chair of the Department of Obstetrics and Gynecology at Weill Cornell Medicine, obstetrician and gynaecologist-in-chief at NewYork-Presbyterian/Weill Cornell, and one of the study’s co-authors, is still advising pregnant patients who decide to get vaccinated to continue to follow current safety guidelines to prevent the spread of the disease.
Dr Riley, Dr Yang, and their colleagues are leading follow-up investigations that are currently enrolling pregnant women who receive the vaccine, as well as vaccinated mothers who are breastfeeding, to assess the antibody response in those groups after vaccination. That information could help guide maternal vaccination strategies moving forward.
The USD 1 million question is: Will the group of women who are now being vaccinated get the same type of protection? We don’t know that yet. Getting those answers is going to be really important, Dr Riley said.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)
NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (Water, Sanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollution, waste management, plastic ban, manual scavenging and sanitation workers and menstrual hygiene.