- Breakthrough infections after vaccinations are a matter of concern: Experts
- Breakthrough infections are mostly symptomatic with fever, cough: Study
- Covishield, Covaxin, Sputnik V are currently approved for use in India
New Delhi: A small-scale study on 113 healthcare workers who had received at least one vaccine dose at a private hospital in Delhi found that 18 tested positive for COVID-19 but all except one had mild symptoms. The study, published in the peer-reviewed journal Diabetes and Metabolic Syndrome: Clinical Research and Reviews on May 3, was conducted on employees of the Fortis Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology in Delhi.
The participants in the study by researchers at Fortis, National Diabetes, Obesity and Cholesterol Foundation, and Diabetes Foundation (India), New Delhi, included doctors, nutritionists, nurses, paramedical workers, and maintenance staff. Of the 113 in the study, 107 had received the second dose of the vaccine. Taken in percentage form, the study found that breakthrough infections — COVID infection in vaccinated individuals — occurred in 15.9 per cent (18 persons) of the vaccinated individuals and 95 per cent had mild symptoms. Of these, 17 incurred the infection after the second dose and one person. Except one person who required hospitalisation, all others had mild COVID-19 disease, the researchers said.
According to the study, of the breakthrough infections (in which a vaccinated individual becomes sick from the same illness that the vaccine is meant to prevent.) in 18 persons, 17 incurred the infection after the second dose. These 17 had got their second dose after a mean of 34.8 days following the first jab. All were symptomatic with fever and half of them had sore throat and cough.
The study covered 123 employees – 75 males, 48 females with mean age 42 — 113 of whom were vaccinated. Of them, 28 people had received the Covaxin vaccine from Bharat Biotech, and 85 the Covishield preventive from the Oxford/AstraZeneca stable.
Covishield, Covaxin and Sputnik V are the three COVID-19 vaccines currently approved for use in India. The three vaccines claim efficacy of 81 per cent, 70 per cent, and 92 per cent respectively. However, Sputnik V has not yet hit the market. The researchers noted that breakthrough infections after adequate vaccinations are a matter of concern but adequate data on these infections is not available.
Vaccines have effectiveness risk of getting COVID-19 infections by 70-90 per cent, and also shield from severe infection. It is possible, therefore, some people who are fully vaccinated against COVID-19 may get COVID-19 infection, the authors of the study said.
They explained that unpublished data from India as well as published reports from other parts of the world indicate these infections are occurring but are rare. In addition, it appears that these breakthrough infections are either asymptomatic or mild in nature, the authors added. The authors acknowledged some limitations of their study: its small sample size, and absence of data on obesity and co-morbid diseases which are important determinants of severity of COVID19. They also did not test asymptomatic infections.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)
NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (Water, Sanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollution, waste management, plastic ban, manual scavenging and sanitation workers and menstrual hygiene.