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Health Ministry Recommends Use Of Dexamethasone Drug For Managing Moderate To Severe COVID-19 Patients

The Dexamethasone drug has been tested in hospitalised patients with COVID-19 in the recovery clinical trial and was found to have benefits for critically ill patients

Health Ministry Recommends Use Of Dexamethasone Drug For Managing Moderate To Severe COVID-19 Patients
Highlights
  • Health ministry has recommended using Dexamethasone drug for COVID-19
  • Dexamethasone will be an alternative to Methylprednisolone: Health Ministry
  • Dexamethasone reduced deaths by 1/3rd in ventilated patients: Oxford

New Delhi: The Union Health Ministry has included the use of Dexamethasone as an alternative to Methylprednisolone for managing moderate to severe COVID-19 cases. In a fresh clinical management protocol for managing COVID-19 cases issued on Saturday (June 27), the ministry stated: “The ministry has updated clinical management protocol for managing COVID-19 cases. Now, it recommends to use Dexamethasone as an alternative choice to Methylprednisolone for managing moderate to severe cases of COVID-19. The change has been made after considering the latest available evidence and expert consultation.”

Also Read: Coronavirus Outbreak Explained: What Is Dexamethasone, The Low-Cost Drug Oxford University Called Breakthrough In COVID-19 Treatment?

According to medical experts, Dexamethasone is a corticosteroid drug used in a wide range of conditions for its anti-inflammatory and immunosuppressant effects.

The move comes when, the Dexamethasone drug has been tested in hospitalised patients with COVID-19 in the recovery clinical trial and was found to have benefits for critically ill patients and has been shown to reduce mortality by about one third for patients on ventilators, and by about one fifth for patients being maintained on oxygen therapy. The drug is also a part of the National List of Essential Medicines (NLEM) and is widely available.

Also Read: 6 Months On, What Do We Know About The Coronavirus Pandemic

On June 17, the University of Oxford in a press statement said that Dexamethasone reduced deaths by one-third in ventilated patients and by one fifth in other patients receiving oxygen only. However, there was no benefit among those patients who did not require respiratory support.

Overall dexamethasone reduced the 28-day mortality rate by 17 percent with a highly significant trend showing greatest benefit among those patients requiring ventilation, University of Oxford in a press statement.

Also Read: All You Need To Know About The First Approved Indian Medicine For Mild-To-Moderate COVID-19 Cases

Based on these results, 1 death would be prevented by treatment of around 8 ventilated patients or around 25 patients requiring oxygen alone, read the statement.

Hence, the Union Health Secretary, Preeti Sudan has forwarded the updated protocol with all States and UTs to make necessary arrangements for availability and use of the updated protocol and drug Dexamethasone at the institutional level also.

Also Read: Coronavirus Prevention: How To Wash Fruits, Vegetables And Other Perishables To Safeguard Them From Virus

World

23,23,25,643Cases
19,46,11,603Active
3,29,58,002Recovered
47,56,038Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 23,23,25,643 and 47,56,038 have died; 19,46,11,603 are active cases and 3,29,58,002 have recovered as on September 28, 2021 at 3:48 am.

India

3,36,97,581 18,795Cases
2,92,2067,414Active
3,29,58,002 26,030Recovered
4,47,373 179Deaths
In India, there are 3,36,97,581 confirmed cases including 4,47,373 deaths. The number of active cases is 2,92,206 and 3,29,58,002 have recovered as on September 28, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

65,44,325

41,396 32

63,64,027

1,38,902 32

Kerala

46,41,587 11,699

1,57,733 6,122

44,59,193 17,763

24,661 58

Karnataka

29,73,899 504

12,833 409

29,23,320 893

37,746 20

Tamil Nadu

26,58,923 1,657

17,261 24

26,06,153 1,662

35,509 19

Andhra Pradesh

20,47,459 618

12,482 566

20,20,835 1,178

14,142 6

Uttar Pradesh

17,09,778 6

176 0

16,86,712 6

22,890

West Bengal

15,66,865 472

7,584 99

15,40,530 556

18,751 15

Delhi

14,38,746 32

366 5

14,13,295 37

25,085

Odisha

10,24,764 444

5,102 214

10,11,482 653

8,180 5

Chhattisgarh

10,05,269 27

282 3

9,91,423 30

13,564

Rajasthan

9,54,316 13

86 9

9,45,276 4

8,954

Gujarat

8,25,872 21

142 9

8,15,648 30

10,082

Madhya Pradesh

7,92,504 8

118 2

7,81,868 6

10,518

Haryana

7,70,825 7

329 6

7,60,686 13

9,810

Bihar

7,25,947 3

57 11

7,16,230 14

9,660

Telangana

6,65,284 216

4,585 27

6,56,785 241

3,914 2

Punjab

6,01,538 38

284 2

5,84,747 35

16,507 1

Assam

6,01,031 412

4,587 42

5,90,593 362

5,851 8

Jharkhand

3,48,198 4

79 1

3,42,986 5

5,133

Uttarakhand

3,43,504 14

218 8

3,35,893 22

7,393

Jammu And Kashmir

3,29,125 117

1,513 1

3,23,190 118

4,422

Himachal Pradesh

2,18,523 209

1,730 16

2,13,124 225

3,669

Goa

1,76,145 50

862 56

1,71,980 106

3,303

Puducherry

1,26,127 37

866 35

1,23,423 72

1,838

Manipur

1,20,000 116

2,111 14

1,16,042 129

1,847 1

Mizoram

90,539 1,846

15,843 358

74,394 1,481

302 7

Tripura

84,085 19

275 3

82,999 22

811

Meghalaya

80,897 108

1,752 125

77,750 230

1,395 3

Chandigarh

65,217 7

44 3

64,354 4

819

Arunachal Pradesh

54,395 43

319 4

53,802 47

274

Sikkim

31,291 25

601 11

30,303 35

387 1

Nagaland

31,167 17

426 19

30,078 35

663 1

Ladakh

20,786 5

148 8

20,431 13

207

Dadra And Nagar Haveli

10,670

0 0

10,666

4

Lakshadweep

10,361

5 0

10,305

51

Andaman And Nicobar Islands

7,619 1

11 2

7,479 3

129

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