Connect with us

Coronavirus Outbreak

ICMR Advises States To Conduct Sero-Survey To Measure Coronavirus Exposure In People Using IgG ELISA Test

The Indian Council of Medical Research has said that antibody IgG test is not useful for detecting acute infection but indicates an episode of SARS-CoV-2 infection in the past

ICMR Advises States To Conduct Sero-Survey To Measure Coronavirus Exposure In People Using IgG ELISA Test
Highlights
  • Antibody tests are useful for detection after 5-7 days of illness: ICMR
  • There is a demand for different COVID-19 tests across the world: ICMR
  • ICMR has offered to provide support to states in carrying of sero-surveys

New Delhi: The Indian Council of Medical Research (ICMR) on Saturday advised States to conduct sero-survey to measure coronavirus exposure in the population using IgG ELISA Test. The ICMR said, “The COVID19 pandemic has so far affected 216 countries and caused more than 59.31 lakh cases and 3.65 lakh deaths worldwide. There is a continuous demand for various types of diagnostic tests by countries all across the globe.”

Also Read: BMC’s Revised Guidelines For COVID-19 Testing: Pregnant Women Likely To Deliver In Next 5 Days To Be Tested

The ICMR said that Real-time i.e. RT-PCR test is considered gold standard frontline test for clinical diagnosis of SARS-CoV-2, causing COVID19. The test is useful only when performed in the acute stage of infection (< 7 days). For several viral infections, antibody tests are useful for disease detection after 5-7 days of illness. Understanding related to antibody tests for COVID19 is evolving and several tests are being developed globally. The ICMR said,

IgG antibodies generally start appearing after two weeks of onset of infection, once the individual has recovered after infection and last for several months. Therefore, the IgG test is not useful for detecting acute infection but indicates episode of SARS-CoV-2 infection in the past. However, detection of IgG antibodies is useful in the following situations: Sero-surveys help to understand the proportion of the population exposed to SARS-CoV-2 infection including asymptomatic individuals. Depending upon the level of sero-prevalence of infection, appropriate public health interventions can be planned and implemented for prevention and control of the disease. Periodic sero-surveys are useful to guide the policy makers. Survey in high risk or vulnerable populations (health care workers, frontline workers, immune-compromised individuals, individuals in containment zones, etc.) to know who has been infected in the past and has now recovered.

It further said that in an attempt to decide the future course of action against the pandemic, ICMR has communicated a detailed plan to all the states to measure coronavirus exposure in general population as well as in high risk populations. This sero-survey will guide appropriate public health intervention. An indicative list of different groups has been provided for adequate representation (Annexure I). The numbers and frequency in different groups to be tested has been entrusted with states depending upon the requirement and situation in that particular area.

Also Read: Quick, Cheap RT-Lamp COVID-19 Test Will Cost Up To Rs. 200, Take Less Than An Hour To Give Result: CSIR

The Annexure I given by ICMR include possible groups/ community/ population based on specific requirement for sero-survey by using IgG Elisa test. The ICMR said,

The sero-survey would be conducted using an IgG ELISA kit. Scientists at ICMR-National Institute of Virology, Pune have developed and validated an indigenous IgG ELISA test for antibody detection for SARS-CoV-2. The test has undergone intense validation in three stages and has been found to have high sensitivity and specificity.

To fast track production and increase availability of the IgG ELISA test, ICMR has transferred this technology to many pharma companies viz. Zydus Cadila, J Mitra & Company, Meril Diagnostics, Voxtur Bio, Trivitron Healthcare, Karwah Enterprises, Avecon Healthcare, etc.

The technology has been transferred to various entities without exclusivity clause and therefore can be further shared with others as per demand and capability. IgG ELISA tests from other USFDA/ CE-IVD/ indigenous sources are also available.

ICMR has offered to provide technical support to States/ UTs, if required, in planning and carrying out sero-surveys using IgG Elisa test kits and also interpreting the results.

Also Read: India Testing 1.1 Lakh COVID-19 Samples In A Day: ICMR Chief

World

24,00,62,413Cases
20,17,73,183Active
3,33,99,961Recovered
48,89,269Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 24,00,62,413 and 48,89,269 have died; 20,17,73,183 are active cases and 3,33,99,961 have recovered as on October 16, 2021 at 4:08 am.

India

3,40,53,573 15,981Cases
2,01,6322,046Active
3,33,99,961 17,861Recovered
4,51,980 166Deaths
In India, there are 3,40,53,573 confirmed cases including 4,51,980 deaths. The number of active cases is 2,01,632 and 3,33,99,961 have recovered as on October 16, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

65,88,429 2,149

33,379 222

64,15,316 1,898

1,39,734 29

Kerala

48,38,811 8,867

95,349 1,072

47,16,728 9,872

26,734 67

Karnataka

29,82,869 470

9,700 93

29,35,238 368

37,931 9

Tamil Nadu

26,84,641 1,245

15,238 213

26,33,534 1,442

35,869 16

Andhra Pradesh

20,59,708 586

6,453 135

20,38,960 712

14,295 9

Uttar Pradesh

17,10,014 6

133 2

16,86,984 8

22,897

West Bengal

15,79,463 451

7,513 63

15,52,997 506

18,953 8

Delhi

14,39,337 26

327 10

14,13,921 36

25,089

Odisha

10,34,276 467

4,817 73

10,21,180 535

8,279 5

Chhattisgarh

10,05,624 10

197 6

9,91,857 16

13,570

Rajasthan

9,54,383 1

40 2

9,45,389 3

8,954

Gujarat

8,26,258 14

212 3

8,15,960 17

10,086

Madhya Pradesh

7,92,675 6

106 5

7,82,046 11

10,523

Haryana

7,71,049 14

116 11

7,60,884 3

10,049

Bihar

7,26,021 5

46 4

7,16,314 1

9,661

Telangana

6,68,722 104

4,056 115

6,60,730 218

3,936 1

Assam

6,05,944 97

3,458 188

5,96,547 284

5,939 1

Punjab

6,01,992 21

228 6

5,85,224 25

16,540 2

Jharkhand

3,48,415 9

130 0

3,43,150 9

5,135

Uttarakhand

3,43,739 10

179 4

3,36,163 6

7,397

Jammu And Kashmir

3,30,885 51

895 40

3,25,564 91

4,426

Himachal Pradesh

2,21,203 90

1,361 26

2,16,125 114

3,717 2

Goa

1,77,410 54

648 31

1,73,423 81

3,339 4

Puducherry

1,27,296 37

611 36

1,24,836 73

1,849

Manipur

1,22,545 113

1,444 0

1,19,208 109

1,893 4

Mizoram

1,11,651 932

13,316 285

97,955 1,211

380 6

Tripura

84,299 4

102 8

83,381 12

816

Meghalaya

82,815 81

893 1

80,490 79

1,432 1

Chandigarh

65,297 2

30 2

64,447 4

820

Arunachal Pradesh

54,964 6

183 19

54,501 25

280

Sikkim

31,739 17

189 35

31,159 51

391 1

Nagaland

31,547 31

228 2

30,645 32

674 1

Ladakh

20,871 4

42 2

20,621 6

208

Dadra And Nagar Haveli

10,675

3 0

10,668

4

Lakshadweep

10,365

1 1

10,313 1

51

Andaman And Nicobar Islands

7,641 1

9 1

7,503 2

129

Coronavirus Outbreak: Full CoverageTesting CentresFAQs

Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Highlights From The 12-Hour Telethon

Leaving No One Behind

Mental Health

Environment

Join Us