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No Proof COVID Second Wave Due To Virus Variants, But It Is Possible: Virologist Shahid Jameel

According to virologist Shahid Jameel, the effectiveness of current COVID-19 vaccines, Covaxin and Covishied, against the double mutant variant has not yet been tested

No Proof COVID Second Wave Due To Virus Variants, But It Is Possible: Virologist Shahid Jameel
Highlights
  • Vaccines won't work unless we take them: Expert
  • Double mutant variant is the coming together of 2 mutations in same virus
  • It is common for mutants to combine: Expert

New Delhi: There is so far no evidence that the second wave of COVID-19 in the country is due to variants of the virus, but it is possible, said noted virologist Shahid Jameel. He, however, stressed that the sharp rise in coronavirus infections seen recently is mainly because people have stopped following COVID-appropriate behaviour. In an interview with PTI, Mr. Jameel, who has won the coveted Shanti Swarup Bhatnagar Prize, said the rollout of vaccines has caused a false sense of security among people.

Also Read: Vaccine Hesitancy Might Pose Threat To Efforts For Ending COVID-19 Pandemic: Study

But vaccines won’t work unless we take them. As of March 25, only 8.1 million people have taken both doses, which is 0.6 per cent of India’s population. Further, 46.4 million people or 3.3 per cent of India’s population have taken only one dose, which gives weak or no protection, he said.

Mr. Jameel further said there is so far no evidence that the second wave is due to variant viruses. “But this is possible”.

“The mortality rate in the second wave appears to be no different. In fact, it appears to be lower than what we saw in August and September 2020, during the first peak,” said Mr. Jameel, who is presently the director of the Trivedi School of Biosciences at Ashoka University.

He said the second wave is mainly because there are enough susceptible people in the country and in the past four months most of the people have stopped following Covid-appropriate behaviour such as wearing masks and avoiding crowded places.

Further, all commercial and recreation activities are back to normal even as the pandemic is still there, Mr. Jameel said.

Registering a steep spike in COVID-19 cases for the 16th day in a row, India on Friday saw 59,118 new coronavirus infections in a day, the highest single-day rise so far this year. The active caseload has breached the 4-lakh mark again after around three-and-half months.

Also Read: COVID-19: UN-Backed Vaccine Delivery Program Warns Of Supply Delays

Asked whether a double mutant variant of the coronavirus is causing this surge in the number of infections, Mr. Jameel said not necessarily, but it can, depending on the properties of the new mutant viruses.

As for the double mutant found in India, we don’t yet know if it is responsible for the surge being observed in some states. Epidemiological correlation is required for that, he said.

A double mutant variant is the coming together of two mutations in the same virus. In the Indian context, this refers to two mutations – L452R and E484Q – both within the receptor-binding domain of the spike protein, coming together, Mr. Jameel explained. Spike proteins play an important role in how these viruses infect their hosts. It is common for mutants to combine, he said.

The UK variant, for example, carries 23 mutations, of which eight are in the Spike protein. The South African variant has nine mutations of which six are in the Spike protein. The Brazil variant has 16 mutations of which 10 are in the spike protein, he said.

Explaining the reason behind such mutations, Mr. Jameel said some of these mutations get ‘selected’ because they offer some advantage to the virus such as better infectivity, ease of transmission from one host to another, evasion of antiviral immunity.

He said the effectiveness of current vaccines, Covaxin and Covishied, against the double mutant variant has not yet been tested. India has detected a new “double mutant” COVID-19 variant of SARS-CoV-2 in Delhi, Maharashtra and some other places in addition to the three “variants of concern” — first noticed in the UK, South Africa and Brazil — that have been found in at least 18 states and union territories. The ministry, however, said it could not be sufficiently established yet if these variants were behind the recent spike in COVID-19 cases in some states.

Also Read: Holi 2021: States And Union Territories Restrict Holi Celebrations Following A Rise In COVID-19 Cases

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

24,06,78,961Cases
20,23,40,977Active
3,34,39,331Recovered
48,98,653Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 24,06,78,961 and 48,98,653 have died; 20,23,40,977 are active cases and 3,34,39,331 have recovered as on October 18, 2021 at 4:17 am.

India

3,40,81,315 13,596Cases
1,89,6946,152Active
3,34,39,331 19,582Recovered
4,52,290 166Deaths
In India, there are 3,40,81,315 confirmed cases including 4,52,290 deaths. The number of active cases is 1,89,694 and 3,34,39,331 have recovered as on October 18, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

65,91,697 1,715

32,230 994

64,19,678 2,680

1,39,789 29

Kerala

48,54,321 7,555

88,186 3,292

47,39,270 10,773

26,865 74

Karnataka

29,83,459 326

9,479 58

29,36,039 380

37,941 4

Tamil Nadu

26,87,092 1,218

14,814 208

26,36,379 1,411

35,899 15

Andhra Pradesh

20,60,472 432

6,034 159

20,40,131 586

14,307 5

Uttar Pradesh

17,10,028 9

119 10

16,87,011 19

22,898

West Bengal

15,80,530 624

7,421 24

15,54,132 634

18,977 14

Delhi

14,39,390 32

320 6

14,13,981 38

25,089

Odisha

10,35,077 443

4,542 68

10,22,250 508

8,285 3

Chhattisgarh

10,05,654 16

183 2

9,91,901 14

13,570

Rajasthan

9,54,390 2

42 2

9,45,394 4

8,954

Gujarat

8,26,290 10

207 6

8,15,997 16

10,086

Madhya Pradesh

7,92,684 5

84 12

7,82,077 17

10,523

Haryana

7,71,076 15

123 9

7,60,904 6

10,049

Bihar

7,26,026 5

48 4

7,16,317 1

9,661

Telangana

6,68,955 122

3,924 55

6,61,093 176

3,938 1

Assam

6,06,468 205

3,436 46

5,97,082 245

5,950 6

Punjab

6,02,035 27

227 8

5,85,264 16

16,544 3

Jharkhand

3,48,430 7

122 1

3,43,173 8

5,135

Uttarakhand

3,43,756 9

178 1

3,36,181 8

7,397

Jammu And Kashmir

3,31,062 95

843 12

3,25,793 107

4,426

Himachal Pradesh

2,21,437 131

1,303 5

2,16,414 125

3,720 1

Goa

1,77,522 60

604 6

1,73,572 62

3,346 4

Puducherry

1,27,396 52

585 13

1,24,961 64

1,850 1

Manipur

1,22,737 104

1,422 0

1,19,418 102

1,897 2

Mizoram

1,12,848 249

11,633 1,143

1,00,829 1,389

386 3

Tripura

84,321 16

104 4

83,401 12

816

Meghalaya

82,953 55

845 32

80,673 86

1,435 1

Chandigarh

65,302 3

25 3

64,457 6

820

Arunachal Pradesh

54,987 7

140 30

54,567 37

280

Sikkim

31,749 4

174 8

31,184 12

391

Nagaland

31,611 40

248 12

30,689 28

674

Ladakh

20,878 2

36 10

20,634 12

208

Dadra And Nagar Haveli

10,676 1

4 1

10,668

4

Lakshadweep

10,365

0 0

10,314

51

Andaman And Nicobar Islands

7,641

9 0

7,503

129

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