Only Way To Decrease Variants Of COVID-19 Is By Increasing Vaccination: Noted Clinical Scientist Gagandeep Kang

Only Way To Decrease Variants Of COVID-19 Is By Increasing Vaccination: Noted Clinical Scientist Gagandeep Kang

According to Scientist Gagandeep Kang, the only way to decrease variants is not to stop vaccination, but to increase it to stop virus circulation and replication
Coronavirus Outbreak, Coronavirus Vaccine, News, Swasth India
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Only Way To Decrease Variants Of COVID-19 Is By Increasing Vaccination: Noted Clinical Scientist Gagandeep Kang"When we are infected or vaccinated, we make antibodies in response to a whole virus or part of a virus, said Scientist Gagandeep Kang
Highlights
  • Vaccination is a preparedness and prevention exercise : Dr Kang
  • Dr Kang said variants are many, but variants that escape immunity are few
  • If viruses are not replicating they cannot mutate: Dr Kang

New Delhi: Stressing that the only way to decrease variants of COVID-19 is by increasing vaccination, prominent clinical scientist Gagandeep Kang said massive inoculation being a mistake is a topic brought up with “pseudo-scientific messy incorrect immunology”. She was reacting to French virologist and Nobel laureate Luc Montagnier’s comments on mass vaccination. Dr Kang said that apparently he did not say all vaccinated people will die in two years, as claimed by some, but he did say that new variants are created through selection imposed by antibodies made through vaccination.

Also Read: COVID-19 Vaccines Highly Effective Against B.1.617.2 Variant That Was First Found In India, Says UK Study

“And he said there will be much stronger infection by variants in vaccinated individuals due to antibody dependent enhancement, massive vaccination is an enormous error, a medical mistake,” Kang tweeted, and termed his claims as “not true”. Dr Kang said,

When we are infected or vaccinated we make antibodies in response to a whole virus or part of a virus. In a viral infection, the body’s immune responses, including antibodies, shut down viral replication and we recover from infection. Massive vaccination being a mistake is a topic brought up with pseudo-scientific messy incorrect immunology that I have addressed previously…, she tweeted.

Calling vaccination an exercise in “preparedness and prevention”, the vaccinologist said the immune response that is made has nothing to fight immediately but “we train the immune system to recognise the virus if and when it comes”.

In a small number of individuals, special, because they are immunocompromised (therefore not usually out & about to spread virus) it is possible that virus replication may be prolonged. In such (rare) cases there may be a development of variants that escape the immune response, she said in another tweet.

Dr Kang said variants are many, but variants that escape immunity are few.

Also Read: Women Can Get COVID Vaccine Anytime After Delivery: Experts

“As the virus spreads through populations and multiplies massively, the few variants that are more capable of escaping immunity that is induced by vaccines will make vaccines somewhat less effective,” she said. While this may be what we are currently seeing with B1.351 and B1.617.2, even there two doses of vaccines protect reasonably (data from Qatar and UK).

The only way to decrease variants is not to stop vaccination, but to increase it to stop virus circulation and replication! she said.

She said it is seen from effectiveness and impact studies that vaccination reduces viral replication in individuals and decreases transmission in communities, effectively decreasing the overall viral load in the community and the world.

Clear and simple- if viruses are not replicating they cannot mutate and become new variants. Vaccinate to decrease viral replication and variants, she said.

She said all vaccines are being evaluated to see that they make high amounts of neutralizing antibodies and they are.

What about with variants because neutralizing antibodies to an older version of the virus might not be enough? This is analogous to the situation with dengue where it is not old and new versions of the virus but four different serotypes that may infect sequentially. With repeat dengue infection, where low levels of antibodies from the first infection with 1 type of virus or vaccination can trigger enhanced/severe disease when a person does get subsequently infected with a type to which there is not good neutralizing antibody, she tweeted.

Noting that with SARS-CoV2 vaccines based on older virus/spike the ability to neutralise new variants is lower but not absent, Kang said vaccines seem to be working.

A booster dose of old or new versions of mRNA vaccines has been shown to broaden the immune response, which is encouraging. We need to continue to study long-term protection, and particularly study the immune response in vaccine breakthrough cases to understand what is happening with immunity and safety. But reassuringly, so far there is no signal, she added.

Also Read: Centre Enables On-Site Registration, Appointment For 18-44 Age Group For COVID-19 Vaccine

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

19,89,21,889Cases
6,44,02,340Active
13,02,83,678Recovered
42,35,871Deaths
Coronavirus has spread to 194 countries. The total confirmed cases worldwide are 19,89,21,889 and 42,35,871 have died; 6,44,02,340 are active cases and 13,02,83,678 have recovered as on August 3, 2021 at 3:55 am.

India

3,17,26,507 30,549Cases
4,04,9588,760Active
3,08,96,354 38,887Recovered
4,25,195 422Deaths
In India, there are 3,17,26,507 confirmed cases including 4,25,195 deaths. The number of active cases is 4,04,958 and 3,08,96,354 have recovered as on August 3, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

63,15,063 4,869

78,700 3,650

61,03,325 8,429

1,33,038 90

Kerala

34,25,473 13,984

1,65,834 2,057

32,42,684 15,923

16,955 118

Karnataka

29,08,284 1,285

24,045 123

28,47,627 1,383

36,612 25

Tamil Nadu

25,63,544 1,957

20,385 139

25,09,029 2,068

34,130 28

Andhra Pradesh

19,70,008 1,546

20,582 437

19,36,016 1,968

13,410 15

Uttar Pradesh

17,08,500 24

646 18

16,85,091 42

22,763

West Bengal

15,29,295 575

10,803 171

15,00,331 734

18,161 12

Delhi

14,36,401 51

538 44

14,10,809 95

25,054

Chhattisgarh

10,02,458 236

1,918 1

9,87,012 234

13,528 3

Odisha

9,79,737 1,032

13,318 820

9,60,386 1,785

6,033 67

Rajasthan

9,53,704 16

241 9

9,44,509 25

8,954

Gujarat

8,24,922 22

251 3

8,14,595 25

10,076

Madhya Pradesh

7,91,862 17

132 7

7,81,217 10

10,513

Haryana

7,69,956 14

703 12

7,59,614 25

9,639 1

Bihar

7,24,917 37

401 34

7,14,872 71

9,644

Telangana

6,45,997 591

8,819 54

6,33,371 643

3,807 2

Punjab

5,99,162 32

473 31

5,82,395 63

16,294

Assam

5,68,257 1,275

12,429 213

5,50,534 1,469

5,294 19

Jharkhand

3,47,223 23

239 15

3,41,855 38

5,129

Uttarakhand

3,42,198 37

574 35

3,34,261 71

7,363 1

Jammu And Kashmir

3,21,725 118

1,254 43

3,16,090 73

4,381 2

Himachal Pradesh

2,06,369 208

1,304 75

2,01,543 132

3,522 1

Goa

1,71,295 90

1,027 16

1,67,118 72

3,150 2

Puducherry

1,21,059 54

944 38

1,18,320 92

1,795

Manipur

99,872 541

9,814 591

88,480 1,120

1,578 12

Tripura

79,026 304

3,104 12

75,167 292

755

Meghalaya

65,939 350

5,843 200

58,987 537

1,109 13

Chandigarh

61,960 6

33 3

61,116 3

811

Arunachal Pradesh

48,565 305

3,508 167

44,823 469

234 3

Mizoram

40,111 748

12,316 127

27,642 618

153 3

Nagaland

28,004 59

1,300 44

26,130 99

574 4

Sikkim

26,880 126

3,323 131

23,211 256

346 1

Ladakh

20,345 5

57 0

20,081 5

207

Dadra And Nagar Haveli

10,650

15 9

10,631 9

4

Lakshadweep

10,207 12

79 4

10,078 8

50

Andaman And Nicobar Islands

7,539

6 1

7,404 1

129

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