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Study Reveals Most Critically Ill Patients With COVID-19 Survive With Standard Treatment

According to a study published in American Journal of Respiratory and Critical Care Medicine, majority of even the sickest patients with COVID-19 get better when they receive existing guideline-supported treatment for respiratory failure

Study Reveals Most Critically Ill Patients With COVID-19 Survive With Standard Treatment
Highlights
  • Harvard Medical School examined 66 critically ill COVID-19 patients
  • Most severe cases of COVID-19 result in Acute Respiratory Distress Syndrome
  • The good news is we have been studying ARDS for over 50 years: Researcher

Massachusetts: Clinicians from two hospitals in Boston report that the majority of even the sickest patients with COVID-19 – those who require ventilators in intensive care units – get better when they receive existing guideline-supported treatment for respiratory failure. The clinicians from Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center discussed COVID-19 patients who are serious to a level that they require ventilators.

The study was published in the American Journal of Respiratory and Critical Care Medicine.

During the COVID-19 pandemic, hospitals around the world have shared anecdotal experiences to help inform the care of affected patients, but such anecdotes do not always reveal the best treatment strategies, and they can even lead to harm.

Also Read: We Need A Plan To Ensure 100 Percent Coverage For The COVID-19 Vaccine, Experts Speak

To provide more reliable information, a team led by C. Corey Hardin, MD, PhD, an Assistant Professor of Medicine at MGH and Harvard Medical School, carefully examined the records of 66 critically ill patients with COVID-19 who experienced respiratory failure and were put on ventilators, making note of their responses to the care they received.

The investigators found that the most severe cases of COVID-19 result in a syndrome called Acute Respiratory Distress Syndrome (ARDS), a life-threatening lung condition that can be caused by a wide range of pathogens.

The good news is we have been studying ARDS for over 50 years and we have a number of effective evidenced-based therapies with which to treat it, said Dr. Hardin.

Also Read: Coronavirus Outbreak Explained: What Are The Four Types Of Vaccines Being Worked On To Fight Coronavirus?

We applied these treatments–such as prone ventilation where patients are turned onto their stomachs–to patients in our study and they responded to them as we would expect patients with ARDS to respond, added Dr Hardin.

Importantly, the death rate among critically ill patients with COVID-19 treated this way -16.7 percent – was not nearly as high as has been reported by other hospitals. Also, over a median follow-up of 34 days, 75.8 percent of patients who were on ventilators were discharged from the intensive care unit.

Based on this, we recommend that clinicians provide evidence-based ARDS treatments to patients with respiratory failure due to COVID-19 and await standardized clinical trials before contemplating novel therapies, said co-lead author and Instructor in Medicine at Mass General, Jehan Alladina.

World

24,06,78,961Cases
20,23,40,977Active
3,34,39,331Recovered
48,98,653Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 24,06,78,961 and 48,98,653 have died; 20,23,40,977 are active cases and 3,34,39,331 have recovered as on October 18, 2021 at 4:17 am.

India

3,40,81,315 13,596Cases
1,89,6946,152Active
3,34,39,331 19,582Recovered
4,52,290 166Deaths
In India, there are 3,40,81,315 confirmed cases including 4,52,290 deaths. The number of active cases is 1,89,694 and 3,34,39,331 have recovered as on October 18, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

65,91,697 1,715

32,230 994

64,19,678 2,680

1,39,789 29

Kerala

48,54,321 7,555

88,186 3,292

47,39,270 10,773

26,865 74

Karnataka

29,83,459 326

9,479 58

29,36,039 380

37,941 4

Tamil Nadu

26,87,092 1,218

14,814 208

26,36,379 1,411

35,899 15

Andhra Pradesh

20,60,472 432

6,034 159

20,40,131 586

14,307 5

Uttar Pradesh

17,10,028 9

119 10

16,87,011 19

22,898

West Bengal

15,80,530 624

7,421 24

15,54,132 634

18,977 14

Delhi

14,39,390 32

320 6

14,13,981 38

25,089

Odisha

10,35,077 443

4,542 68

10,22,250 508

8,285 3

Chhattisgarh

10,05,654 16

183 2

9,91,901 14

13,570

Rajasthan

9,54,390 2

42 2

9,45,394 4

8,954

Gujarat

8,26,290 10

207 6

8,15,997 16

10,086

Madhya Pradesh

7,92,684 5

84 12

7,82,077 17

10,523

Haryana

7,71,076 15

123 9

7,60,904 6

10,049

Bihar

7,26,026 5

48 4

7,16,317 1

9,661

Telangana

6,68,955 122

3,924 55

6,61,093 176

3,938 1

Assam

6,06,468 205

3,436 46

5,97,082 245

5,950 6

Punjab

6,02,035 27

227 8

5,85,264 16

16,544 3

Jharkhand

3,48,430 7

122 1

3,43,173 8

5,135

Uttarakhand

3,43,756 9

178 1

3,36,181 8

7,397

Jammu And Kashmir

3,31,062 95

843 12

3,25,793 107

4,426

Himachal Pradesh

2,21,437 131

1,303 5

2,16,414 125

3,720 1

Goa

1,77,522 60

604 6

1,73,572 62

3,346 4

Puducherry

1,27,396 52

585 13

1,24,961 64

1,850 1

Manipur

1,22,737 104

1,422 0

1,19,418 102

1,897 2

Mizoram

1,12,848 249

11,633 1,143

1,00,829 1,389

386 3

Tripura

84,321 16

104 4

83,401 12

816

Meghalaya

82,953 55

845 32

80,673 86

1,435 1

Chandigarh

65,302 3

25 3

64,457 6

820

Arunachal Pradesh

54,987 7

140 30

54,567 37

280

Sikkim

31,749 4

174 8

31,184 12

391

Nagaland

31,611 40

248 12

30,689 28

674

Ladakh

20,878 2

36 10

20,634 12

208

Dadra And Nagar Haveli

10,676 1

4 1

10,668

4

Lakshadweep

10,365

0 0

10,314

51

Andaman And Nicobar Islands

7,641

9 0

7,503

129

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