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COVID-19: ICMR Issues Advisory On CRISPR Technology-Based SARS Cov-2 Test

CRISPR (clustered regulatory interspaced short palindromic) SARS CoV-2 test has been developed by the Council of Scientific and Industrial Research, Delhi and does not require further RT-PCR based confrimation

COVID-19: ICMR Issues Advisory On CRISPR Technology-Based SARS Cov-2 Test
Highlights
  • The test has been approved by the Drugs Controller General of India
  • CRISPR SARS-CoV-2 tests gives confirmed positive or negative: Manufacturers
  • CRISPR SARS-CoV-2 testing should follow standard RT-PCR guidelines: ICMR

New Delhi: The Indian Council of Medical Research (ICMR) on Thursday issued an advisory on the CRISPR SARS CoV-2 test that has been approved by the Drugs Controller General of India for COVID-19 detection. CRISPR (clustered regulatory interspaced short palindromic) SARS CoV-2 test is a new diagnostic method based on CRISPR-Cas9 technology to identify and target the genetic material of SARS-CoV-2 virus.

Also Read: COVID-19 Pandemic Provided Learning Curve To Be More Resilient, Prepared For Future: Dr Harsh Vardhan

The test has been developed by the Council of Scientific and Industrial Research (CSIR)-Institute of Genomics and Integrative Biology (IGIB), Delhi and has been validated by the Department of Atomic Energy (DAE) – National Center for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru.

The test has been approved by DCGI for use in India which works by identifying SARS-CoV-2 virus strain and uses a Thermal Cycler instead of a qPCR machine for conducting the test.

As claimed by the manufacturer, no further RT-PCR based confirmation is required for samples that are confirmed as positives or negatives by the CRISPR SARS-CoV-2 test.

Also Read: IIT-Kharagpur Develops Low-Cost, Portable COVID-19 Testing Device

Specimen collection and transfer of sample for CRISPR SARS-CoV-2 test must be performed using appropriate PPE, the ICMR advised.

It is further advised that testing with CRISPR SARS-CoV-2 test be carried out under appropriate biosafety (BSL2 level) precautions, following the standard RT-PCR guidelines laid down by ICMR.

Existing government, private laboratories already approved by ICMR for SARS-CoV-2 RT-PCR based testing may use this new CRISPR test if the laboratory desires to do so.

No further approval is required from the ICMR for existing laboratories.

New laboratories intending to initiate molecular testing of SARS-CoV-2 testing by any method will be required to seek approvals as per the standard process laid down by ICMR and NABL before initiating any kind of molecular testing, said the ICMR.

“Any prescription for RT-PCR, CRISPR, TRUENAT, CBNAAT may be considered equivalent,” it added.

Also Read: India In ‘Extremely Comfortable Position’ In Terms Of Oxygen Availability: Health Ministry

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

26,27,61,966Cases
22,35,18,265Active
3,40,28,506Recovered
52,15,195Deaths
Coronavirus has spread to 196 countries. The total confirmed cases worldwide are 26,27,61,966 and 52,15,195 have died; 22,35,18,265 are active cases and 3,40,28,506 have recovered as on December 1, 2021 at 3:56 am.

India

3,45,96,776 8,954Cases
99,0231,520Active
3,40,28,506 10,207Recovered
4,69,247 267Deaths
In India, there are 3,45,96,776 confirmed cases including 4,69,247 deaths. The number of active cases is 99,023 and 3,40,28,506 have recovered as on December 1, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

66,35,658 678

11,226 299

64,83,435 942

1,40,997 35

Kerala

51,41,814 4,723

44,314 824

50,57,368 5,370

40,132 177

Karnataka

29,96,148 291

6,445 462

29,51,492 745

38,211 8

Tamil Nadu

27,26,917 720

8,244 47

26,82,192 758

36,481 9

Andhra Pradesh

20,72,909 184

2,149 47

20,56,318 134

14,442 3

Uttar Pradesh

17,10,399 12

89 3

16,87,399 8

22,911 1

West Bengal

16,16,083 705

7,731 2

15,88,866 694

19,486 13

Delhi

14,40,934 34

287 2

14,15,549 32

25,098

Odisha

10,49,108 228

2,188 23

10,38,509 203

8,411 2

Chhattisgarh

10,06,813 34

318 0

9,92,902 34

13,593

Rajasthan

9,54,785 15

193 6

9,45,637 9

8,955

Gujarat

8,27,475 40

275 13

8,17,108 27

10,092

Madhya Pradesh

7,93,170 20

119 7

7,82,523 27

10,528

Haryana

7,71,709 17

163 2

7,61,492 19

10,054

Bihar

7,26,223 4

36 3

7,16,524 7

9,663

Telangana

6,75,994 196

3,591 10

6,68,411 184

3,992 2

Assam

6,16,852 144

2,625 30

6,08,124 109

6,103 5

Punjab

6,03,279 21

325 4

5,86,352 22

16,602 3

Jharkhand

3,49,244 12

98 3

3,44,006 9

5,140

Uttarakhand

3,44,255 28

141 9

3,36,706 19

7,408

Jammu And Kashmir

3,36,852 171

1,625 1

3,30,751 172

4,476

Himachal Pradesh

2,27,195 102

834 10

2,22,513 91

3,848 1

Goa

1,78,928 38

284 8

1,75,260 30

3,384

Mizoram

1,35,175 365

3,751 54

1,30,927 415

497 4

Puducherry

1,28,924 31

284 12

1,26,768 43

1,872

Manipur

1,25,205 36

649 6

1,22,579 40

1,977 2

Tripura

84,805 14

81 3

83,900 10

824 1

Meghalaya

84,480 19

294 9

82,713 9

1,473 1

Chandigarh

65,465 9

65 7

64,580 2

820

Arunachal Pradesh

55,276 3

35 0

54,961 3

280

Sikkim

32,242 9

124 3

31,715 6

403

Nagaland

32,122 13

133 7

31,293 20

696

Ladakh

21,578 38

276 26

21,088 12

214

Dadra And Nagar Haveli

10,683

1 0

10,678

4

Lakshadweep

10,394

24 0

10,319

51

Andaman And Nicobar Islands

7,683

6 2

7,548 2

129

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