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Pfizer, Moderna Vaccines Cut COVID-19 Risk By 91 Per Cent: Study

The study was designed to measure the risks and rates of COVID-19 infection among those on the front lines of the pandemic including doctors, nurses, and first responders

Pfizer, Moderna Vaccines Cut COVID-19 Risk By 91 Per Cent: Study

Washington: People who receive COVID-19 vaccines by Pfizer and Moderna are up to 91 per cent less likely to develop the disease, according to a US study which also suggests that the preventives reduce the severity of symptoms and duration in those who still get an infection. The research, published in the New England Journal of Medicine on June 30, is among the first to show the benefits of mRNA vaccines even among those who experience breakthrough infections — testing positive after immunisation.

Also Read: COVID-19: Pregnant And Thinking Of Getting Vaccinated? Here’s What Government Guidelines Say About Safety, Side-Effects

The mRNA vaccines by Pfizer and Moderna contain genetic instructions for our cells to make the spike protein of the SARS-CoV-2, which the virus uses to infect and enter the human cells. Our immune system then builds an immune response against the spike protein, and learns how to fight off the coronavirus if we encounter it in future.

One of the unique things about this study is that it measured the secondary benefits of the vaccines, said study co-author Sarang Yoon, an assistant professor at the University of Utah, US.

The study was designed to measure the risks and rates of infection among those on the front lines of the pandemic — doctors, nurses, and first responders.

These are the people who are getting exposure to the virus day in and day out, and the vaccine protected them against getting the disease. Those who unfortunately got COVID-19 despite being vaccinated were still better off than those who didn’t, he added.

The study found that mRNA COVID-19 vaccines were 91 per cent effective in reducing risk for infection once participants were “fully” vaccinated, two weeks after the second dose.

Also Read: India Administers Over 35 Crore Doses In 170 Days, Second Highest Globally, Says Union Health Ministry

The researchers also found that the vaccines are 81 per cent effective in reducing risk for infection after “partial” immunisation, two weeks after the first dose was given. The study recruited 3,975 participants at eight sites in the US.

Participants submitted samples for COVID-19 testing on a weekly basis for 17 weeks between December 13, 2020 and April 10, 2021. Only 204 (5 per cent) of the participants eventually tested positive for SARS-CoV-2, the virus that causes COVID-19. Of these, 156 were unvaccinated, 32 had an indeterminate vaccine status, and 16 were fully or partially vaccinated.

The fully or partially vaccinated participants who developed breakthrough had milder symptoms than those who were unvaccinated. In those who developed a breakthrough infection, the presence of fever was reduced by 58 per cent per cent among vaccinated people, and the days spent sick in bed were reduced by 60 per cent.

Detection of the virus was reduced by 70 per cent percent among those with breakthrough infections, from 8.9 days to 2.7 days. These findings also suggest that fully or partially vaccinated individuals who get COVID-19 might be less likely to spread the virus to others. The researchers found that infected study participants who had been fully or partially vaccinated when infected had 40 per cent less detectable virus in the nose and did so for six fewer days compared to those who were unvaccinated. “I hope these findings reassure the public that mRNA COVID-19 vaccines are safe and protect us from this severe disease,” Yoon added.

Also Read: COVID-19 Vaccines Effective Against Delta Variant Of Novel Coronavirus, Says Dr Anthony Fauci

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

22,70,55,138Cases
18,97,86,461Active
3,25,98,424Recovered
46,70,253Deaths
Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 22,70,55,138 and 46,70,253 have died; 18,97,86,461 are active cases and 3,25,98,424 have recovered as on September 17, 2021 at 5:36 am.

India

3,33,81,728 34,403Cases
3,39,0563,867Active
3,25,98,424 37,950Recovered
4,44,248 320Deaths
In India, there are 3,33,81,728 confirmed cases including 4,44,248 deaths. The number of active cases is 3,39,056 and 3,25,98,424 have recovered as on September 17, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

65,11,525 3,595

52,893 310

63,20,310 3,240

1,38,322 45

Kerala

44,46,228 22,182

1,86,754 4,559

42,36,309 26,563

23,165 178

Karnataka

29,65,191 1,108

16,202 282

29,11,434 808

37,555 18

Tamil Nadu

26,40,361 1,693

16,756 120

25,88,334 1,548

35,271 25

Andhra Pradesh

20,34,786 1,367

14,708 105

20,06,034 1,248

14,044 14

Uttar Pradesh

17,09,628 23

193 11

16,86,549 11

22,886 1

West Bengal

15,59,567 707

8,025 25

15,32,922 725

18,620 7

Delhi

14,38,373 28

409 5

14,12,880 22

25,084 1

Odisha

10,18,298 580

5,335 105

10,04,845 681

8,118 4

Chhattisgarh

10,04,988 31

352 2

9,91,077 29

13,559

Rajasthan

9,54,230 4

103 1

9,45,173 5

8,954

Gujarat

8,25,677 22

149 0

8,15,446 22

10,082

Madhya Pradesh

7,92,374 7

119 5

7,81,738 12

10,517

Haryana

7,70,697 9

327 8

7,60,562 17

9,808

Bihar

7,25,864 12

72 6

7,16,134 6

9,658

Telangana

6,62,785 259

5,282 43

6,53,603 301

3,900 1

Punjab

6,01,180 30

314 11

5,84,399 38

16,467 3

Assam

5,97,074 468

5,381 15

5,85,914 479

5,779 4

Jharkhand

3,48,102 6

102 8

3,42,867 14

5,133

Uttarakhand

3,43,330 20

284 12

3,35,657 32

7,389

Jammu And Kashmir

3,27,466 170

1,421 72

3,21,630 98

4,415

Himachal Pradesh

2,16,430 127

1,568 82

2,11,215 206

3,647 3

Goa

1,75,183 95

699 1

1,71,195 96

3,289

Puducherry

1,25,170 107

963 63

1,22,380 42

1,827 2

Manipur

1,17,913 216

2,614 7

1,13,478 219

1,821 4

Tripura

83,787 31

427 26

82,553 56

807 1

Meghalaya

78,958 229

1,804 140

75,784 86

1,370 3

Mizoram

76,591 1,121

13,888 85

62,449 1,202

254 4

Chandigarh

65,168 4

31 2

64,319 2

818

Arunachal Pradesh

53,990 47

536 9

53,183 56

271

Sikkim

30,802 64

775 28

29,648 36

379

Nagaland

30,763 32

505 14

29,610 44

648 2

Ladakh

20,631 6

41 1

20,383 5

207

Dadra And Nagar Haveli

10,670

5 0

10,661

4

Lakshadweep

10,353

4 0

10,298

51

Andaman And Nicobar Islands

7,595 3

15 2

7,451 1

129

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