Researchers Find Three Reasons Behind Coronavirus Causing Silent Hypoxia

Researchers Find Three Reasons Behind Coronavirus Causing Silent Hypoxia

Silent hypoxia is a condition when oxygen levels in the body are abnormally low, which can cause major damage to the vital organs of the body if gone undetected for a long period of time
Coronavirus Outbreak, News
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Researchers Find Three Reasons Behind Coronavirus Causing Silent HypoxiaThe researchers used computer models and comparisons with real COVID-19 patient data
Highlights
  • COVID-19 patients sometimes show no symptoms of shortness of breath
  • Hypoxia's ability to quietly inflict damage is why it's been coined silent
  • Coronavirus is believed to first damage the lungs: Research

Washington: Boston University biomedical engineers and collaborators from the University of Vermont have begun to crack one of the most life-threatening mysteries behind the relationship between silent hypoxia and coronavirus following different scenarios. According to Science Daily, researchers are still unaware of the fact that tells the reason behind why the lungs of a COVID patient stop providing oxygen to the bloodstream. All the findings would be done with the help of computer models and comparisons with real patient data.

Also Read: Healthcare Workers, People Aged Above 65 Years Will Be Given COVID Vaccine On Priority: Dr. Harsh Vardhan

Silent hypoxia is a condition when oxygen levels in the body are abnormally low, which can cause major damage to the vital organs of the body if gone undetected for a long period of time.

Despite experiencing dangerously low levels of oxygen, many people infected with severe cases of COVID-19 sometimes show no symptoms of shortness of breath or difficulty breathing. Hypoxia’s ability to quietly inflict damage is why it’s been coined “silent.”

Also Read: Coronavirus Outbreak Explained: What Is A Pulse Oximeter And Why Is It Becoming A Tool Against COVID-19?

According to the research, coronavirus is believed to first damage the lungs restraining them to function properly. Those tissues then lose oxygen, causing silent hypoxia. But exactly how that effect occurs is under the table till now. “We didn’t know [how this] was physiologically possible,” says Bela Suki, one of the authors of the study, when many of the patients showed almost no signs of abnormalities when they were undertaken for a lung scan.

The results of the research, attained after a deep study with the help of a computer model is been published in Nature Communications which unveils the study by the lead author of the new study Jacob Herrmann. It states,

Silent hypoxia is likely caused by a combination of biological mechanisms that may occur simultaneously in the lungs of COVID-19 patients.

The good thing that researchers revealed is the ability of the lungs to constrict the blood vessels in absence of sufficient oxygen caused by an infection which then forces blood to flow through lung tissue crammed with oxygen, throughout the body.

Also Read: ‘How Smoking Worsens COVID-19 Infection Decoded’: Scientists

According to Jacob Herrmann,

Preliminary clinical data have suggested that the lungs of some COVID-19 patients had lost the ability to restrict blood flow to already damaged tissue, and in contrast, were potentially opening up those blood vessels even more, which is hard to measure on a CT scan.

The second scenario observed by the researchers with the help of a computer model found that silent Hypnoxia can provoke when the lining of blood vessels are inflamed from the COVID-infection.

The last step was to find if COVID-19 interferes with the normal ratio of air-to-blood flow, vital for lungs to function normally. The researchers found that the mismatched air-to-blood flow ratio is a common symptom in many respiratory illnesses, like asthma and this mismatch doesn’t appear injured or abnormal on lung scans.

Also Read: Coronavirus Outbreak Explained: What Is A Cytokine Storm And How Is It Fuelling COVID-19? Experts Answer

In all, the researchers concluded that a combination of all three factors can contribute to abnormal oxygen in some COVID-19 patients, and to attain perfection in making choices about treating patients, the clinical are suggested using measures like ventilation and supplemental oxygen.

According to the report provided by Science Daily, a number of interventions are currently being studied to have a more informed study about the combinations varying from patient to patient. One of them is a low-tech intervention called prone positioning that flips patients over onto their stomachs, allowing for the back part of the lungs to pull in more oxygen and evening out the mismatched air-to-blood ratio.

Also Read: COVID-19 Pandemic Explained: What Is Reproduction (R) Number And Why Does It Matter?

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

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World

19,66,15,634Cases
6,33,31,644Active
12,90,85,240Recovered
41,98,750Deaths
Coronavirus has spread to 194 countries. The total confirmed cases worldwide are 19,66,15,634 and 41,98,750 have died; 6,33,31,644 are active cases and 12,90,85,240 have recovered as on July 30, 2021 at 4:07 am.

India

3,15,72,344 44,230Cases
4,05,155 1,315Active
3,07,43,972 42,360Recovered
4,23,217 555Deaths
In India, there are 3,15,72,344 confirmed cases including 4,23,217 deaths. The number of active cases is 4,05,155 and 3,07,43,972 have recovered as on July 30, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths
Maharashtra

62,90,156 7,242

81,933 3,980

60,75,888 11,032

1,32,335 190

Kerala

33,49,365 22,064

1,55,327 5,287

31,77,453 16,649

16,585 128

Karnataka

29,01,247 2,052

23,277 685

28,41,479 1,332

36,491 35

Tamil Nadu

25,55,664 1,859

21,207 314

25,00,434 2,145

34,023 28

Andhra Pradesh

19,62,049 2,107

21,279 280

19,27,438 1,807

13,332 20

Uttar Pradesh

17,08,373 60

784 16

16,84,834 44

22,755

West Bengal

15,26,539 766

11,300 70

14,97,116 822

18,123 14

Delhi

14,36,144 51

554 19

14,10,541 70

25,049

Chhattisgarh

10,01,781 130

2,086 140

9,86,175 270

13,520

Odisha

9,74,132 1,615

15,276 489

9,53,088 2,039

5,768 65

Rajasthan

9,53,622 17

259 9

9,44,410 26

8,953

Gujarat

8,24,829 27

268 6

8,14,485 33

10,076

Madhya Pradesh

7,91,796 18

130 0

7,81,153 18

10,513

Haryana

7,69,858 30

712 10

7,59,516 17

9,630 3

Bihar

7,24,719 46

481 1

7,14,596 42

9,642 3

Telangana

6,43,716 623

9,188 126

6,30,732 746

3,796 3

Punjab

5,99,005 58

553 6

5,82,162 60

16,290 4

Assam

5,64,030 1,299

14,114 385

5,44,695 1,664

5,221 20

Jharkhand

3,47,105 56

259 22

3,41,720 34

5,126

Uttarakhand

3,41,982 48

669 3

3,33,952 51

7,361

Jammu And Kashmir

3,21,207 181

1,144 5

3,15,686 175

4,377 1

Himachal Pradesh

2,05,728 229

1,098 145

2,01,110 84

3,520

Goa

1,70,900 90

1,077 5

1,66,679 93

3,144 2

Puducherry

1,20,725 98

972 49

1,17,961 49

1,792

Manipur

96,824 1,000

10,895 27

84,408 1,016

1,521 11

Tripura

78,059 271

3,640 221

73,665 488

754 4

Meghalaya

63,745 731

5,750 294

56,933 423

1,062 14

Chandigarh

61,948 5

37 1

61,102 4

809

Arunachal Pradesh

47,477 335

4,252 49

43,000 383

225 1

Mizoram

37,171 764

11,862 252

25,168 511

141 1

Nagaland

27,653 67

1,299 51

25,798 114

556 4

Sikkim

26,132 276

3,297 180

22,498 92

337 4

Ladakh

20,324 4

60 4

20,057 8

207

Dadra And Nagar Haveli

10,643 1

36 5

10,603 6

4

Lakshadweep

10,162 7

70 6

10,042 13

50

Andaman And Nicobar Islands

7,534 3

10 3

7,395

129

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