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Third Dose Of COVID-19 Vaccine Can Boost Effectiveness Against Omicron To 88%, UK Studies Show

Covid booster dose: The findings compiled in a report by the UK Health Security Agency (UKSHA) show significantly higher protection provided by third dose of COVID-19 vaccine

Third Dose Of COVID-19 Vaccine Can Boost Effectiveness Against Omicron To 88%, UK Studies Show
A booster dose substantially increases immunity and lowers the odds of being hospitalised with COVID-19 infection, show studies
  • Vaccine effectiveness drops to 52% against Omicron: Expert
  • The drop is witnessed 6 months post the second dose of a COVID-19 vaccine
  • Booster shot can boost the effectiveness from 52% to 88%: Report

London: A third dose of COVID-19 vaccine can provide up to 88 per cent protection against hospitalisation from infection by the Omicron variant of coronavirus, according to early results from studies conducted in the UK. The findings compiled in a report by the UK Health Security Agency (UKSHA) show significantly higher protection provided by third vaccine dose against the highly mutated variant first identified in Botswana and South Africa in November, compared to two doses. Eric Topol, professor of molecular medicine, and director of the Scripps Research Translational Institute in the US noted that vaccine effectiveness drops to 52 per cent against Omicron around six months after taking the second shot of a COVID-19 vaccine.

Also Read: COVID-19: Vaccination For 15-18 Age Group Starts Today Amid Covid Surge

However, a booster dose substantially increases immunity and lowers the odds of being hospitalised with COVID-19 infection.

“That’s a big boost of protection for 3rd dose vaccine vs hospitalisation from Omicron infection. Vaccine effectiveness increased from 52 per cent (due to 2-dose waning after 6 months) to 88 per cent after the 3rd dose,” Mr Topol tweeted on Sunday.

“It’s pretty impressive that vaccines directed to the ancestral strain spike from 2 years ago, with the virus that’s evolved through more than 290 million confirmed cases, and now to the hyper-mutated Omicron, have preserved efficacy of near 90 per cent vs severe disease with a 3rd shot,” he said in another tweet.

Also Read: Covaxin Has Shown Good Immune Response In Children During Trials, Says NTAGI Chief

The UKHSA report cited two studies which examined the association between both variant and vaccination status and risk of hospitalisation.

The first study is based on approximately half a million Omicron cases, and includes all age groups while the second one uses a smaller dataset and is restricted to ages 18 and over.

The first study confirms the previous finding of reduced overall risk of hospitalisation for Omicron compared to Delta variant.

Both the studies found a substantial reduction in risk of hospitalisation for Omicron cases after three doses of vaccine compared to those who are unvaccinated.

Despite the estimated reduction in hospitalisation risk and preserved vaccine effectiveness against hospitalisation, the study authors noted that there may still be large numbers of admissions to hospital.

Also Read: Opinion: Have A Healthy New Year 2022, Strengthen Your Defence Against COVID-19

The risk of hospital admission from emergency departments with Omicron was approximately one-third of that for Delta.

The report shows that vaccine effectiveness against symptomatic disease continues to be lower for Omicron than for Delta with waning by 10 weeks after dose 3.

After three doses of vaccine, the risk of hospitalisation for a symptomatic case identified with Omicron through community testing was estimated to be reduced by 68 per cent when compared to similar individuals with the variant who were not vaccinated.

Combined with the protection against becoming a symptomatic case, this gives a vaccine effectiveness against hospitalisation of 88 per cent (78 to 93 per cent) for Omicron after three doses of vaccine, the UKHSA report added.

Also Read: Recap 2021: Health, Hygiene And Sanitation In Focus In The Second Year Of The Covid-19 Pandemic

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol have been working towards a clean and healthy India since 2014 via Banega Swachh India initiative, which is helmed by Campaign Ambassador Amitabh Bachchan. The campaign aims to highlight the inter-dependency of humans and the environment, and of humans on one another with the focus on One Health, One Planet, One Future – Leaving No One Behind. It stresses on the need to take care of, and consider, everyone’s health in India – especially vulnerable communities – the LGBTQ populationindigenous people, India’s different tribes, ethnic and linguistic minorities, people with disabilities, migrants, geographically remote populations, gender and sexual minorities. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign will continue to raise awareness on the same along with focussing on the importance of nutrition and healthcare for women and children, fight malnutrition, mental wellbeing, self care, science and health, adolescent health & gender awareness. Along with the health of people, the campaign has realised the need to also take care of the health of the eco-system. Our environment is fragile due to human activity,  that is not only over-exploiting available resources, but also generating immense pollution as a result of using and extracting those resources. The imbalance has also led to immense biodiversity loss that has caused one of the biggest threats to human survival – climate change. It has now been described as a “code red for humanity.” The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene. Banega Swasth India will also be taking forward the dream of Swasth Bharat, the campaign feels that only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and the country can become a Swasth or healthy India.

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