- Earlier studies said COVID-19 antibodies wane after few months of infection
- While antibodies wane, memory cells of immune system protect the body
- Once vaccines develop, they will provide long-term protection: Experts
Melbourne: People who have recovered from the novel coronavirus infection have immune memory to protect against reinfection for at least eight months, according to a new study which provides strong evidence for the likelihood that COVID-19 vaccines will work for long periods. While earlier studies have shown that antibodies against the coronavirus wane after the first few months of infection, raising concerns that people may lose immunity quickly, the new research, published in the journal Science Immunology, puts these concerns to rest.
According to the scientists, including those from Monash University in Australia, specific cells within the immune system called memory B cells, “remembers” infection by the virus, and if re-exposed to the virus, triggers a protective immune response through rapid production of protective antibodies.
In the study, the researchers recruited a cohort of 25 COVID-19 patients and took 36 blood samples from them from Day 4 post-infection to Day 242 post-infection. The scientists found that antibodies against the virus started to drop off after 20 days post-infection.
However, they said all patients continued to have memory B cells that recognised one of two components of the virus — the spike protein which helps the virus enter host cells, and the nucleocapsid proteins. Based on their analysis, the researchers said these virus-specific memory B cells were stably present as far as eight months after infection.
The scientists believe the findings give hope to the efficacy of any vaccine against the virus, and also explains why there have been very few examples of genuine reinfection across the millions of those who have tested positive for the virus globally.
These results are important because they show, definitively, that patients infected with the COVID-19 virus do in fact retain immunity against the virus and the disease. This has been a black cloud hanging over the potential protection that could be provided by any COVID-19 vaccine and gives real hope that, once a vaccine or vaccines are developed, they will provide long-term protection, said study co-author Menno van Zelm, from the Monash University Department of Immunology and Pathology.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)
NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (Water, Sanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollution, waste management, plastic ban, manual scavenging and sanitation workers and menstrual hygiene.