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COVID-19 Outbreak: New Coronavirus Strains In The Country Could Be More Dangerous, Says Dr Randeep Guleria, Director, AIIMS- Delhi

According to AIIMS Director Dr Randeep Guleria, the new strain of SARS-CoV-2 found in Maharashtra could be more transmissible than the existing version strain already floating in the country and could cause re-infections

COVID-19 Outbreak: New Coronavirus Strains In The Country Could Be More Dangerous, Says Dr Randeep Guleria, Director, AIIMS- Delhi
  • It is natural for a virus to mutate: Dr Guleria
  • New strains have emerged in the country: Maharashtra COVID Task Force
  • COVID-appropriate behaviour needs to be maintained all the time: Dr Guleria

New Delhi: According to the Ministry of Health and Family Welfare (MoHFW), the country has been recording a spike in daily active cases of COVID-19 since February 18. On Monday (February 22), active coronavirus cases increased by 4,421 in 24 hours – a spike of three per cent – to cross the 1.5 lakh mark for the first time in 17 days and register the steepest overall increase since end-November. The spike in national numbers comes as five states – Maharashtra, Kerala, Punjab, Chhattisgarh and Madhya Pradesh, report an increase in daily numbers, says the central government. The reason behind this spike could be new strains of mutated coronavirus that have been emerging across the country and almost 240 such variants have come into the view, says the Maharashtra COVID Task Force. So as witnessed in UK and other European countries is this a second wave of the pandemic for India?

Also Read: N440K And E484Q, Two New Variants Of Novel Coronavirus Detected In India: Health Ministry

Dr Randeep Guleria, Director, All India Institute of Medical Science (AIIMS) in Delhi highlights that coronavirus, like all other viruses, has a tendency to mutate as it multiplies. While some mutations are inconsequential, some may make the virus more contagious or dangerous or both, he said. However, he also said that the negligence on part of people in following preventive measures like not wearing masks, washing hands and maintaining social distance, may also lead to a surge in cases.

In the last many months, we have seen that the coronavirus has been mutating and we have seen strains becoming very infectious like the ones that emerged in United Kingdom, South Africa and in Brazil. But I think the surge is also related to multiple factors including the COVID appropriate behaviour which has also come down. Because of this, we are seeing a spike in various places in the country. This is something we need to be concerned about and take aggressive actions so that we are able to contain it right now rather than having an increasing number of cases in the rest of the country, said Dr Guleria.

Talking about the rising cases in Amravati, Maharashtra and other districts where clusters of people are testing positive and the positivity rate (percentage of people who test positive out of all of the tests done) in these areas have gone up exponentially, Dr Guleria said,

Clusters of cases occur when people do not follow the preventive measures properly. If you are not wearing a mask or not maintaining physical distance or not washing hands regularly, then you will have a high risk of getting the infection. And if you are giving a chance to the virus to spread, it will cause clusters of cases.

Emphasizing the need for adopting COVID-19 norms in order to prevent the spread of new strains, Dr Guleria said,

I think we need to go back to the things we were doing during the early days of the pandemic- aggressive measures of testing, contact tracing and isolating infections so that the chain of transmission is broken. It is not being done as aggressively as it was being done in the past. We have to understand that the virus is going to change and we should not take things casually.

Also Read: COVID Antibodies Are Transferred From Pregnant Women To Their Babies

Explaining that such setbacks in the fight against the pandemic are expected Dr Guleria said that complacency should be avoided at all cost. He busted the myth of “herd immunity developing in the country” and asserted,

Even if you look at the data collected during sero-surveillance studies across the country, it clearly suggests that the number of people who have got the immunity across the country is still not enough to cause herd immunity. Only 20-25 per cent of the population in India has developed immunity against COVID-19, however, you need at least 80 per cent of people have the antibodies to say that we are reaching herd immunity.

Dr Guleria further explained that herd immunity should be given much importance because it is dependent upon the immunity developed against the original virus but when there are numerous mutations that have occurred in the virus, then the immune response will fall and thus the person who already has the antibodies gets reinfection.

We have to look for other strategies to defeat the pandemic rather than waiting for herd immunity, he said.

As one of the strategies, Dr Guleria recommends increasing genome sequencing of the coronavirus which is the process of studying the genetic make-up of the virus to identify mutations. He emphasised on having more data on virus genomes to be able to find what all strains of coronavirus are floating in different parts of the country. This data will not only help the policymakers and health authorities in making effective strategies to contain the transmission but will also provide vital insights for developing efficient vaccines that can cover the new variants, he said.

Also Read: ‘Casual And Careless’ Behaviour Of People Resulted In Rise In COVID-19 Cases: Indore Health Official

Immune Escape Mechanism Of New Strains Is A Cause Of Concern

According to Dr Guleria, new variants of coronavirus develop immune escape mechanism which helps the virus to bypass the immune response that the human body has already developed because of previous COVID-19 infection or vaccines. Because of this, the virus is able to cause reinfections despite the body having antibodies. He further said,

Data suggests that some of the vaccines may still be effective although the efficacy may come down. We need to be careful because more of the new strains may emerge when we start vaccinating more and more people which would cause it to mutate and try and develop immune escape mechanism.

Dr Guleria added that there is always a possibility of another wave of infection facing the country. He said,

We are at a good positing right now but if we have new strains that can cause reinfections, there is a chance of another wave of infections.

Also Read: COVID-19 Variant N440K Spreading More In Southern States: Centre For Cellular And Molecular Biology

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene


Coronavirus has spread to 195 countries. The total confirmed cases worldwide are 24,36,58,646 and 49,48,410 have died; 20,51,42,869 are active cases and 3,35,67,367 have recovered as on October 25, 2021 at 4:04 am.


3,41,89,774 14,306Cases
3,35,67,367 18,762Recovered
4,54,712 443Deaths
In India, there are 3,41,89,774 confirmed cases including 4,54,712 deaths. The number of active cases is 1,67,695 and 3,35,67,367 have recovered as on October 25, 2021 at 2:30 am.

State Details

State Cases Active Recovered Deaths

66,02,961 1,410

27,506 128

64,35,439 1,520

1,40,016 18


49,15,331 8,538

77,964 3,191

48,08,775 11,366

28,592 363


29,85,986 388

8,740 203

29,39,239 586

38,007 5

Tamil Nadu

26,95,216 1,127

13,034 246

26,46,163 1,358

36,019 15

Andhra Pradesh

20,63,577 400

5,102 120

20,44,132 516

14,343 4

Uttar Pradesh

17,10,095 13

103 9

16,87,093 4


West Bengal

15,86,455 989

7,882 151

15,59,518 828

19,055 10


14,39,603 37

320 14

14,14,192 51



10,38,411 447

4,185 33

10,25,917 410

8,309 4


10,05,847 20

219 11

9,92,056 31



9,54,402 2

31 1

9,45,417 3



8,26,418 16

164 4

8,16,167 20


Madhya Pradesh

7,92,749 9

85 6

7,82,141 3



7,71,157 16

127 12

7,60,981 4



7,26,058 4

38 2

7,16,359 2



6,70,274 135

3,950 34

6,62,377 168

3,947 1


6,08,589 139

3,857 111

5,98,759 244

5,973 6


6,02,209 20

229 2

5,85,429 22



3,48,627 35

224 22

3,43,268 13



3,43,821 6

163 6

3,36,259 11

7,399 1

Jammu And Kashmir

3,31,638 72

866 4

3,26,343 68


Himachal Pradesh

2,22,638 69

1,496 82

2,17,406 149

3,736 2


1,77,886 34

545 29

1,73,983 63



1,27,735 61

467 10

1,25,411 49

1,857 2


1,23,292 63

931 30

1,20,450 89

1,911 4


1,17,419 158

8,080 863

1,08,927 1,016

412 5


84,389 5

98 3

83,475 8



83,371 49

639 56

81,286 102

1,446 3


65,323 2

28 1

64,475 1


Arunachal Pradesh


132 10

54,677 10



31,900 32

200 5

31,306 27



31,712 5

243 7

30,790 12



20,904 5

37 1

20,659 6


Dadra And Nagar Haveli


4 0





0 0



Andaman And Nicobar Islands


6 2

7,513 2


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