- In-hospital deaths among patients with secondary infection is high: Expert
- The study assessed 375 patients with severe COVID-19 from March to May 2020
- More research is needed to better understand secondary infections: Expert
New York: People with severe COVID-19 who also had secondary infections in the bloodstream were sicker, had longer hospital stays, and worse health outcomes, according to a study that may lead to new treatment strategies. The research, published in the journal Clinical Infectious Diseases, is the first to assess the microbiology, risk factors, and outcomes in hospitalised patients with severe COVID-19 and secondary bloodstream infections. In the study, researchers from Rutgers University in the US assessed 375 patients diagnosed with severe COVID-19 from March to May 2020.
Also Read: 5 Per Cent Of COVID-19 Cases To Be Tested For Whole Genome Sequencing Due To New Virus Strain In UK: Centre
They sampled 128 cases from the group that had secondary bloodstream infections — 92 per cent of which were bacterial infections.
These patients were more likely to have altered mental status, lower percent oxygen saturation, septic shock and to be admitted to the intensive care unit compared to those without bloodstream infections, said study co-lead author Pinki Bhatt from Rutgers University.
According to the scientists, patients who needed more advanced types of supplemental oxygen upon hospital admission had higher odds of secondary bloodstream infections. The researchers said the in-hospital mortality rate for these patients was more than 50 per cent, but added that these deaths were associated with — not caused by — the condition.
They believe these infections in COVID-19 patients may have contributed to the severity of illness, or it may reflect other underlying physiological and immunological complications of COVID-19. According to the study, 80 per cent of all the patients in the study received antimicrobials at some point during hospitalisation, including those who did not have bloodstream infections.
This likely reflects clinicians’ inclination to administer antimicrobials given the limited information on the natural course of this novel disease, Ms. Bhatt said.
However, she added that further studies are needed to better understand when to suspect and treat secondary bloodstream infections in severe COVID-19.
Also Read: Hyderabad Based Start-Up Develops Robot Disinfectant ‘ACCORD’
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)
NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (Water, Sanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollution, waste management, plastic ban, manual scavenging and sanitation workers and menstrual hygiene.